3k2i: Difference between revisions

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{{Seed}}
[[Image:3k2i.jpg|left|200px]]


<!--
==Human Acyl-coenzyme A thioesterase 4==
The line below this paragraph, containing "STRUCTURE_3k2i", creates the "Structure Box" on the page.
<StructureSection load='3k2i' size='340' side='right'caption='[[3k2i]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3k2i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K2I FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr>
{{STRUCTURE_3k2i| PDB=3k2i |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k2i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k2i OCA], [https://pdbe.org/3k2i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k2i RCSB], [https://www.ebi.ac.uk/pdbsum/3k2i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k2i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACOT4_HUMAN ACOT4_HUMAN] Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH (By similarity). Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k2/3k2i_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k2i ConSurf].
<div style="clear:both"></div>


===Human Acyl-coenzyme A thioesterase 4===
==See Also==
 
*[[Thioesterase 3D structures|Thioesterase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3K2I is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K2I OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Palmitoyl-CoA hydrolase]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Berg, S Van Den.]]
[[Category: Berglund H]]
[[Category: Berglund, H.]]
[[Category: Bountra C]]
[[Category: Bountra, C.]]
[[Category: Collins R]]
[[Category: Collins, R.]]
[[Category: Edwards AM]]
[[Category: Edwards, A M.]]
[[Category: Flodin S]]
[[Category: Flodin, S.]]
[[Category: Flores A]]
[[Category: Flores, A.]]
[[Category: Graslund S]]
[[Category: Graslund, S.]]
[[Category: Hammarstrom M]]
[[Category: Hammarstrom, M.]]
[[Category: Johansson A]]
[[Category: Johansson, A.]]
[[Category: Johansson I]]
[[Category: Johansson, I.]]
[[Category: Kallas A]]
[[Category: Kallas, A.]]
[[Category: Karlberg T]]
[[Category: Karlberg, T.]]
[[Category: Kotenyova T]]
[[Category: Kotenyova, T.]]
[[Category: Kotzsch A]]
[[Category: Kotzsch, A.]]
[[Category: Kraulis P]]
[[Category: Kraulis, P.]]
[[Category: Markova N]]
[[Category: Markova, N.]]
[[Category: Moche M]]
[[Category: Moche, M.]]
[[Category: Nielsen TK]]
[[Category: Nielsen, T K.]]
[[Category: Nordlund P]]
[[Category: Nordlund, P.]]
[[Category: Nyman T]]
[[Category: Nyman, T.]]
[[Category: Persson C]]
[[Category: Persson, C.]]
[[Category: Roos AK]]
[[Category: Roos, A K.]]
[[Category: Schuler H]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Schutz P]]
[[Category: Schuler, H.]]
[[Category: Siponen MI]]
[[Category: Schutz, P.]]
[[Category: Svensson L]]
[[Category: Siponen, M I.]]
[[Category: Thorsell AG]]
[[Category: Svensson, L.]]
[[Category: Tresaugues L]]
[[Category: Thorsell, A G.]]
[[Category: Van Den Berg S]]
[[Category: Tresaugues, L.]]
[[Category: Wahlberg E]]
[[Category: Wahlberg, E.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Welin M]]
[[Category: Welin, M.]]
[[Category: Wisniewska M]]
[[Category: Wisniewska, M.]]
[[Category: Alpha/beta hydrolase fold seven-stranded beta-sandwich]]
[[Category: Hydrolase]]
[[Category: Peroxisome]]
[[Category: Polymorphism]]
[[Category: Serine esterase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 21 10:43:05 2009''
Retrieved from "https://proteopedia.org/3k2i"