1d76: Difference between revisions

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New page: left|200px<br /><applet load="1d76" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d76, resolution 1.300Å" /> '''CRYSTAL AND MOLECUL...
 
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[[Image:1d76.gif|left|200px]]<br /><applet load="1d76" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1d76, resolution 1.300&Aring;" />
'''CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT CONTAINING A 2-AMINO ADENINE MODIFICATION: THE RELATIONSHIP BETWEEN CONFORMATION, PACKING, AND HYDRATION IN Z-DNA HEXAMERS'''<br />


==Overview==
==CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT CONTAINING A 2-AMINO ADENINE MODIFICATION: THE RELATIONSHIP BETWEEN CONFORMATION, PACKING, AND HYDRATION IN Z-DNA HEXAMERS==
The crystal and molecular structure of d(CGUA'CG)2 (where A' is, 2-aminoadenine) has been determined and refined to an R factor of 13.8%, for data 8.0-1.3 A. The structure is very similar to the original Z-DNA, structures with the sequence d(CGCGCG)2 [Gessner, R. V., Frederick, C. A., Quigley, G. J., Rich, A., &amp; Wang, A. H.-J. (1989) J. Biol. Chem. 264, 7921] and shows that the substitution of 2-aminoadenine-uracil base pairs, in the two central steps is consistent with Z-DNA formation. In addition, we show how waters mediating intermolecular interactions may help to, explain the ZI-ZII conformational pattern found in many Z-DNA structures.
<StructureSection load='1d76' size='340' side='right'caption='[[1d76]], [[Resolution|resolution]] 1.30&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1d76]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D76 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D76 FirstGlance]. <br>
1D76 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1D76 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1AP:2,6-DIAMINOPURINE+NUCLEOTIDE'>1AP</scene></td></tr>
==Reference==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d76 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d76 OCA], [https://pdbe.org/1d76 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d76 RCSB], [https://www.ebi.ac.uk/pdbsum/1d76 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d76 ProSAT]</span></td></tr>
Crystal and molecular structure of a DNA fragment containing a 2-aminoadenine modification: the relationship between conformation, packing, and hydration in Z-DNA hexamers., Schneider B, Ginell SL, Jones R, Gaffney B, Berman HM, Biochemistry. 1992 Oct 13;31(40):9622-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=1390739 1390739]
</table>
[[Category: Protein complex]]
__TOC__
[[Category: Berman, H.M.]]
</StructureSection>
[[Category: Gaffney, B.]]
[[Category: Large Structures]]
[[Category: Ginell, S.L.]]
[[Category: Berman HM]]
[[Category: Jones, R.]]
[[Category: Gaffney B]]
[[Category: Schneider, B.]]
[[Category: Ginell SL]]
[[Category: double helix]]
[[Category: Jones R]]
[[Category: modified]]
[[Category: Schneider B]]
[[Category: z-dna]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 02:38:43 2007''

Latest revision as of 06:50, 7 February 2024

CRYSTAL AND MOLECULAR STRUCTURE OF A DNA FRAGMENT CONTAINING A 2-AMINO ADENINE MODIFICATION: THE RELATIONSHIP BETWEEN CONFORMATION, PACKING, AND HYDRATION IN Z-DNA HEXAMERS

1d76, resolution 1.30Å

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