3kb3: Difference between revisions
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New page: '''Unreleased structure''' The entry 3kb3 is ON HOLD Authors: X. Edward Zhou, Karsten Melcher, Fen-Fen Soon, Ley-Moy Ng, Yong Xu, Kelly M. Suino-Powell, Amanda Kovach, Jun Li, H. Eric X... |
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==Crystal structure of abscisic acid-bound PYL2 in complex with HAB1== | |||
<StructureSection load='3kb3' size='340' side='right'caption='[[3kb3]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3kb3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KB3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KB3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A8S:(2Z,4E)-5-[(1S)-1-HYDROXY-2,6,6-TRIMETHYL-4-OXOCYCLOHEX-2-EN-1-YL]-3-METHYLPENTA-2,4-DIENOIC+ACID'>A8S</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kb3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kb3 OCA], [https://pdbe.org/3kb3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kb3 RCSB], [https://www.ebi.ac.uk/pdbsum/3kb3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kb3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PYL2_ARATH PYL2_ARATH] Receptor for abscisic acid (ABA) required for ABA-mediated responses such as stomatal closure and germination inhibition. Inhibits the activity of group-A protein phosphatases type 2C (PP2Cs) when activated by ABA.<ref>PMID:19898420</ref> <ref>PMID:19893533</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kb/3kb3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kb3 ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[Abscisic acid receptor 3D structures|Abscisic acid receptor 3D structures]] | |||
*[[Protein phosphatase 3D structures|Protein phosphatase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Arabidopsis thaliana]] | |||
[[Category: Large Structures]] | |||
[[Category: Kovach A]] | |||
[[Category: Li J]] | |||
[[Category: Melcher K]] | |||
[[Category: Ng L-M]] | |||
[[Category: Soon F-F]] | |||
[[Category: Suino-Powell KM]] | |||
[[Category: Xu HE]] | |||
[[Category: Xu Y]] | |||
[[Category: Zhou XE]] | |||
Latest revision as of 10:16, 21 February 2024
Crystal structure of abscisic acid-bound PYL2 in complex with HAB1
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