1l9g: Difference between revisions
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New page: left|200px<br /><applet load="1l9g" size="450" color="white" frame="true" align="right" spinBox="true" caption="1l9g, resolution 2.5Å" /> '''CRYSTAL STRUCTURE OF ... |
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== | ==CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA== | ||
<StructureSection load='1l9g' size='340' side='right'caption='[[1l9g]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
[[Category: | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1l9g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1L9G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1L9G FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1l9g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1l9g OCA], [https://pdbe.org/1l9g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1l9g RCSB], [https://www.ebi.ac.uk/pdbsum/1l9g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1l9g ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/1l9g TOPSAN]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/UDGA_THEMA UDGA_THEMA] Removes uracil bases that are present in DNA as a result of either deamination of cytosine or misincorporation of dUMP instead of dTMP. Can remove uracil from double-stranded DNA containing either a U/G or U/A base pair as well as from single-stranded DNA.<ref>PMID:10339434</ref> <ref>PMID:11267830</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l9/1l9g_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1l9g ConSurf]. | |||
<div style="clear:both"></div> | |||
==See Also== | |||
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Thermotoga maritima]] | [[Category: Thermotoga maritima]] | ||
[[Category: Almo | [[Category: Almo SC]] | ||
[[Category: Bresnik | [[Category: Bresnik A]] | ||
[[Category: Burley | [[Category: Burley SK]] | ||
[[Category: Chance | [[Category: Chance MR]] | ||
[[Category: Dodatko | [[Category: Dodatko T]] | ||
[[Category: Franklin | [[Category: Franklin WA]] | ||
[[Category: Rajashankar KR]] | |||
[[Category: Rajashankar | [[Category: Sandigursky M]] | ||
[[Category: Sandigursky | [[Category: Thirumuruhan RA]] | ||
[[Category: Thirumuruhan | |||
Latest revision as of 06:27, 13 August 2026
CRYSTAL STRUCTURE OF URACIL-DNA GLYCOSYLASE FROM T. MARITIMA
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