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New page: left|200px<br /><applet load="1d96" size="450" color="white" frame="true" align="right" spinBox="true" caption="1d96, resolution 2.000Å" /> '''MOLECULAR STRUCTURE...
 
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[[Image:1d96.gif|left|200px]]<br /><applet load="1d96" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1d96, resolution 2.000&Aring;" />
'''MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA'''<br />


==Overview==
==MOLECULAR STRUCTURE OF R(GCG)D(TATACGC): A DNA-RNA HYBRID HELIX JOINED TO DOUBLE HELICAL DNA==
The molecule r(GCG)d(TATACGC) is self-complementary and forms two DNA--RNA, hybrid segments surrounding a central region of double helical DNA; its, molecular structure has been solved by X-ray analysis. All three parts of, the molecule adopt a conformation which is close to that seen in the, 11-fold RNA double helix. The conformation of the ribonucleotides is, partly determined by water molecules bridging between the ribose O2', hydroxyl group and cytosine O2. The hybrid-DNA duplex junction contains no, structural discontinuities. However, the central DNA TATA sequence has, some structural irregularities.
<StructureSection load='1d96' size='340' side='right'caption='[[1d96]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1d96]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1D96 FirstGlance]. <br>
1D96 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1D96 OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1d96 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1d96 OCA], [https://pdbe.org/1d96 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1d96 RCSB], [https://www.ebi.ac.uk/pdbsum/1d96 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1d96 ProSAT]</span></td></tr>
==Reference==
</table>
Molecular structure of r(GCG)d(TATACGC): a DNA--RNA hybrid helix joined to double helical DNA., Wang AH, Fujii S, van Boom JH, van der Marel GA, van Boeckel SA, Rich A, Nature. 1982 Oct 14;299(5884):601-4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=6181416 6181416]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Boeckel, S.A.A.Van.]]
[[Category: Large Structures]]
[[Category: Boom, J.H.Van.]]
[[Category: Fujii S]]
[[Category: Fujii, S.]]
[[Category: Rich A]]
[[Category: Marel, G.A.Van.Der.]]
[[Category: Van Boeckel SAA]]
[[Category: Rich, A.]]
[[Category: Van Boom JH]]
[[Category: Wang, A.H.J.]]
[[Category: Van Der Marel GA]]
[[Category: a-dna/rna]]
[[Category: Wang AH-J]]
[[Category: double helix]]
 
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