3g8t: Difference between revisions

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{{Seed}}
[[Image:3g8t.jpg|left|200px]]


<!--
==Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P==
The line below this paragraph, containing "STRUCTURE_3g8t", creates the "Structure Box" on the page.
<StructureSection load='3g8t' size='340' side='right'caption='[[3g8t]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3g8t]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3G8T FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A2M:2-O-METHYLADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>A2M</scene>, <scene name='pdbligand=GLP:GLUCOSAMINE+6-PHOSPHATE'>GLP</scene>, <scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3g8t| PDB=3g8t |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3g8t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3g8t OCA], [https://pdbe.org/3g8t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3g8t RCSB], [https://www.ebi.ac.uk/pdbsum/3g8t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3g8t ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SNRPA_HUMAN SNRPA_HUMAN] Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5'-UGCAC-3' motif in vitro.<ref>PMID:9848648</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/g8/3g8t_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3g8t ConSurf].
<div style="clear:both"></div>


===Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P===
==See Also==
 
*[[Nucleoprotein 3D structures|Nucleoprotein 3D structures]]
 
*[[Ribozyme 3D structures|Ribozyme 3D structures]]
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== References ==
The line below this paragraph, {{ABSTRACT_PUBMED_19228039}}, adds the Publication Abstract to the page
<references/>
(as it appears on PubMed at http://www.pubmed.gov), where 19228039 is the PubMed ID number.
__TOC__
-->
</StructureSection>
{{ABSTRACT_PUBMED_19228039}}
 
==About this Structure==
3G8T is a 12 chains structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3G8T OCA].
 
==Reference==
<ref group="xtra">PMID:19228039</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Cochrane, J C.]]
[[Category: Large Structures]]
[[Category: Lipchock, S V.]]
[[Category: Synthetic construct]]
[[Category: Smith, K D.]]
[[Category: Cochrane JC]]
[[Category: Strobel, S A.]]
[[Category: Lipchock SV]]
[[Category: Acetylation]]
[[Category: Smith KD]]
[[Category: Catalytic rna]]
[[Category: Strobel SA]]
[[Category: Mrna processing]]
[[Category: Mrna splicing]]
[[Category: Nucleus]]
[[Category: Phosphoprotein]]
[[Category: Ribonucleoprotein]]
[[Category: Rna binding protein/rna complex]]
[[Category: Rna-binding]]
[[Category: Spliceosome]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov  4 10:56:01 2009''

Latest revision as of 09:53, 21 February 2024

Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P

3g8t, resolution 3.00Å

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