1dnm: Difference between revisions

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New page: left|200px<br /><applet load="1dnm" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dnm, resolution 2.500Å" /> '''CRYSTAL STRUCTURE A...
 
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[[Image:1dnm.gif|left|200px]]<br /><applet load="1dnm" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1dnm, resolution 2.500&Aring;" />
'''CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)'''<br />


==Overview==
==CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)==
The crystal structure of the dodecanucleotide d(CGCAAGCTGGCG) has been, determined to a resolution of 2.5 A and refined to an R factor of 19.3%, for 1710 reflections. The sequence crystallizes as a B-type double helix, with two G(anti).A(syn) base pairs. These are stabilized by three-center, hydrogen bonds to pyrimidines that induce perturbations in base-pair, geometry. The central AGCT region of the helix has a wide (greater than 6, A) minor groove.
<StructureSection load='1dnm' size='340' side='right'caption='[[1dnm]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[1dnm]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DNM FirstGlance]. <br>
1DNM is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1DNM OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dnm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dnm OCA], [https://pdbe.org/1dnm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dnm RCSB], [https://www.ebi.ac.uk/pdbsum/1dnm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dnm ProSAT]</span></td></tr>
==Reference==
</table>
Crystal structure and sequence-dependent conformation of the A.G mispaired oligonucleotide d(CGCAAGCTGGCG)., Webster GD, Sanderson MR, Skelly JV, Neidle S, Swann PF, Li BF, Tickle IJ, Proc Natl Acad Sci U S A. 1990 Sep;87(17):6693-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=2395870 2395870]
__TOC__
[[Category: Protein complex]]
</StructureSection>
[[Category: Li, B.F.]]
[[Category: Large Structures]]
[[Category: Neidle, S.]]
[[Category: Li BF]]
[[Category: Sanderson, M.R.]]
[[Category: Neidle S]]
[[Category: Skelly, J.V.]]
[[Category: Sanderson MR]]
[[Category: Swann, P.F.]]
[[Category: Skelly JV]]
[[Category: Tickle, I.J.]]
[[Category: Swann PF]]
[[Category: Webster, G.D.]]
[[Category: Tickle IJ]]
[[Category: b-dna]]
[[Category: Webster GD]]
[[Category: double helix]]
[[Category: mismatched]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 03:23:55 2007''

Latest revision as of 06:56, 7 February 2024

CRYSTAL STRUCTURE AND SEQUENCE-DEPENDENT CONFORMATION OF THE A.G MIS-PAIRED OLIGONUCLEOTIDE D(CGCAAGCTGGCG)

1dnm, resolution 2.50Å

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