3ksn: Difference between revisions
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New page: '''Unreleased structure''' The entry 3ksn is ON HOLD Authors: Ahmadpour, F, Gloyd, M, Guarne, A, Stewart, G, Pathania, R, Brown, ED Description: Crystal structure of the lipoprotein lo... |
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==Crystal structure of the lipoprotein localization factor, LolA== | |||
<StructureSection load='3ksn' size='340' side='right'caption='[[3ksn]], [[Resolution|resolution]] 1.65Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ksn]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KSN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KSN FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ksn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ksn OCA], [https://pdbe.org/3ksn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ksn RCSB], [https://www.ebi.ac.uk/pdbsum/3ksn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ksn ProSAT]</span></td></tr> | |||
'' | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/LOLA_ECOLI LOLA_ECOLI] Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane); the inner membrane retention signal functions at the release step.<ref>PMID:11758943</ref> May act as a regulator of the RCS-phosphorelay signal transduction pathway.<ref>PMID:11758943</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ks/3ksn_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ksn ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Ahmadpour F]] | |||
[[Category: Brown ED]] | |||
[[Category: Gloyd M]] | |||
[[Category: Guarne A]] | |||
[[Category: Pathania R]] | |||
[[Category: Stewart G]] | |||
Latest revision as of 08:22, 6 September 2023
Crystal structure of the lipoprotein localization factor, LolA
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