2w4e: Difference between revisions

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{{Seed}}
[[Image:2w4e.jpg|left|200px]]


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==Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans==
The line below this paragraph, containing "STRUCTURE_2w4e", creates the "Structure Box" on the page.
<StructureSection load='2w4e' size='340' side='right'caption='[[2w4e]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2w4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4e OCA], [https://pdbe.org/2w4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4e RCSB], [https://www.ebi.ac.uk/pdbsum/2w4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4e ProSAT]</span></td></tr>
{{STRUCTURE_2w4e|  PDB=2w4e  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q9RSC1_DEIRA Q9RSC1_DEIRA]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/2w4e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w4e ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Nudix pyrophosphatases are a well represented protein family in the Deinococcus radiodurans genome. These hydrolases, which are known to be enzymatically active towards nucleoside diphosphate derivatives, play a role in cleansing the cell pool of potentially deleterious damage products. Here, the structure of DR2204, the only ADP-ribose pyrophosphatase in the D. radiodurans genome that is known to be active towards flavin adenosine dinucleotide (FAD), is presented at 2.0 angstrom resolution.


===STRUCTURE OF AN N-TERMINALLY TRUNCATED NUDIX HYDROLASE DR2204 FROM DEINOCOCCUS RADIODURANS===
Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans.,Goncalves AM, Fioravanti E, Stelter M, McSweeney S Acta Crystallogr Sect F Struct Biol Cryst Commun. 2009 Nov 1;65(Pt, 11):1083-7. Epub 2009 Oct 13. PMID:19923723<ref>PMID:19923723</ref>


From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2w4e" style="background-color:#fffaf0;"></div>


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==See Also==
The line below this paragraph, {{ABSTRACT_PUBMED_19923723}}, adds the Publication Abstract to the page
*[[ADP-ribose pyrophosphatase 3D structures|ADP-ribose pyrophosphatase 3D structures]]
(as it appears on PubMed at http://www.pubmed.gov), where 19923723 is the PubMed ID number.
*[[Nudix hydrolase 3D structures|Nudix hydrolase 3D structures]]
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== References ==
{{ABSTRACT_PUBMED_19923723}}
<references/>
 
__TOC__
==About this Structure==
</StructureSection>
2W4E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4E OCA].
[[Category: Deinococcus radiodurans R1]]
 
[[Category: Large Structures]]
==Reference==
[[Category: Fioravanti E]]
<ref group="xtra">PMID:19923723</ref><references group="xtra"/>
[[Category: Goncalves AMD]]
[[Category: ADP-ribose diphosphatase]]
[[Category: McSweeney S]]
[[Category: Deinococcus radiodurans]]
[[Category: Stelter M]]
[[Category: Fioravanti, E.]]
[[Category: Goncalves, A M.D.]]
[[Category: Mcsweeney, S.]]
[[Category: Stelter, M.]]
[[Category: Adp-ribose pyrophosphatase]]
[[Category: Hydrolase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  2 10:09:06 2009''

Latest revision as of 10:07, 9 May 2024

Structure of an N-terminally truncated Nudix hydrolase DR2204 from Deinococcus radiodurans

2w4e, resolution 2.00Å

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