3hiv: Difference between revisions

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{{Seed}}
[[Image:3hiv.jpg|left|200px]]


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==Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue==
The line below this paragraph, containing "STRUCTURE_3hiv", creates the "Structure Box" on the page.
<StructureSection load='3hiv' size='340' side='right'caption='[[3hiv]], [[Resolution|resolution]] 2.14&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3hiv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HIV FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.14&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=TXN:(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-3,6-DIHYDRO-9H-PURIN-9-YL)-2-({[(S)-({(3R,4R)-4-({[(S)-{[(2R,3R,4R,5R)-5-(2-AMINO-6-OXO-6,8-DIHYDRO-9H-PURIN-9-YL)-2-(HYDROXYMETHYL)-4-METHOXYTETRAHYDROFURAN-3-YL]OXY}(HYDROXY)PHOSPHORYL]OXY}METHYL)-1-[(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)METHYL]PYRROLIDIN-3-YL}OXY)(HYDROXY)PHOSPHORYL]OXY}METHYL)-4-METHOXYTETRAHYDROFURAN-3-YL+3-HYDROXYPROPYL+HYDROGEN+(S)-PHOSPHATE'>TXN</scene></td></tr>
{{STRUCTURE_3hiv|  PDB=3hiv  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hiv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hiv OCA], [https://pdbe.org/3hiv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hiv RCSB], [https://www.ebi.ac.uk/pdbsum/3hiv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hiv ProSAT]</span></td></tr>
 
</table>
===Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue===
== Function ==
 
[https://www.uniprot.org/uniprot/Q2QEH4_SAPOF Q2QEH4_SAPOF]
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_19920175}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 19920175 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/hi/3hiv_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_19920175}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3HIV is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Saponaria_officinalis Saponaria officinalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HIV OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3hiv ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:19920175</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Saponaria officinalis]]
[[Category: Saponaria officinalis]]
[[Category: RRNA N-glycosylase]]
[[Category: Almo SC]]
[[Category: Almo, S C.]]
[[Category: Ho M]]
[[Category: Ho, M.]]
[[Category: Schramm VL]]
[[Category: Schramm, V L.]]
[[Category: Sturm MB]]
[[Category: Sturm, M B.]]
[[Category: Hydrolase]]
[[Category: Hydrolase/hydrolase inhibitor complex]]
[[Category: Plant defense]]
[[Category: Protein synthesis inhibitor]]
[[Category: Ribosome inactivating protein]]
[[Category: Rip]]
[[Category: Toxin]]
[[Category: Transition state]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec  9 14:59:00 2009''

Latest revision as of 10:00, 21 February 2024

Crystal structure of Saporin-L1 in complex with the trinucleotide inhibitor, a transition state analogue

3hiv, resolution 2.14Å

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