3kw6: Difference between revisions

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{{Seed}}
[[Image:3kw6.jpg|left|200px]]


<!--
==Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A==
The line below this paragraph, containing "STRUCTURE_3kw6", creates the "Structure Box" on the page.
<StructureSection load='3kw6' size='340' side='right'caption='[[3kw6]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3kw6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KW6 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_3kw6| PDB=3kw6 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kw6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kw6 OCA], [https://pdbe.org/3kw6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kw6 RCSB], [https://www.ebi.ac.uk/pdbsum/3kw6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kw6 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PRS8_HUMAN PRS8_HUMAN] The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kw/3kw6_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kw6 ConSurf].
<div style="clear:both"></div>


===Crystal Structure of a domain of 26S proteasome regulatory subunit 8 from homo sapiens. Northeast Structural Genomics Consortium target id HR3102A===
==See Also==
 
*[[Proteasome 3D structures|Proteasome 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3KW6 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KW6 OCA].
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Acton, T B.]]
[[Category: Large Structures]]
[[Category: Baran,M C]]
[[Category: Acton TB]]
[[Category: Cunningham, K.]]
[[Category: Baran MC]]
[[Category: Hunt, J F.]]
[[Category: Cunningham K]]
[[Category: Janjua, H.]]
[[Category: Hunt JF]]
[[Category: Liu, J.]]
[[Category: Janjua H]]
[[Category: Montelione, G T.]]
[[Category: Liu J]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: Owens, L.]]
[[Category: Owens L]]
[[Category: Seetharaman, J.]]
[[Category: Seetharaman J]]
[[Category: Su, M.]]
[[Category: Su M]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Wang, D.]]
[[Category: Wang D]]
[[Category: Xiao, R.]]
[[Category: Xiao R]]
[[Category: Acetylation]]
[[Category: Atp-binding]]
[[Category: Cytoplasm]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Nucleotide-binding]]
[[Category: Nucleus]]
[[Category: Polymorphism]]
[[Category: Proteasome]]
[[Category: Protein structure initiative]]
[[Category: Psi-2]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 23 10:26:32 2009''
Retrieved from "https://proteopedia.org/3kw6"