1v4p: Difference between revisions

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New page: left|200px<br /><applet load="1v4p" size="450" color="white" frame="true" align="right" spinBox="true" caption="1v4p, resolution 1.45Å" /> '''Crystal structure of...
 
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[[Image:1v4p.gif|left|200px]]<br /><applet load="1v4p" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1v4p, resolution 1.45&Aring;" />
'''Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3'''<br />


==About this Structure==
==Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3==
1V4P is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii] with ZN as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Alanine--tRNA_ligase Alanine--tRNA ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.1.1.7 6.1.1.7] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA].  
<StructureSection load='1v4p' size='340' side='right'caption='[[1v4p]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[1v4p]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1V4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1V4P FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1v4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1v4p OCA], [https://pdbe.org/1v4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1v4p RCSB], [https://www.ebi.ac.uk/pdbsum/1v4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1v4p ProSAT], [https://www.topsan.org/Proteins/RSGI/1v4p TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALAXS_PYRHO ALAXS_PYRHO] Functions in trans to edit the amino acid moiety from mischarged charged Ser-tRNA(Ala). Has little activity against Gly-tRNA(Ala).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v4/1v4p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1v4p ConSurf].
<div style="clear:both"></div>


==Reference==
==See Also==
Crystal structure of alanyl-tRNA synthetase editing-domain homolog (PH0574) from a hyperthermophile, Pyrococcus horikoshii OT3 at 1.45 A resolution., Ishijima J, Uchida Y, Kuroishi C, Tuzuki C, Takahashi N, Okazaki N, Yutani K, Miyano M, Proteins. 2006 Mar 1;62(4):1133-7. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16374837 16374837]
*[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]]
[[Category: Alanine--tRNA ligase]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Single protein]]
[[Category: Ishijima J]]
[[Category: Ishijima, J.]]
[[Category: Yutani K]]
[[Category: RSGI, RIKEN.Structural.Genomics/Proteomics.Initiative.]]
[[Category: Yutani, K.]]
[[Category: ZN]]
[[Category: alanine-trna ligase]]
[[Category: alanyl-trna synthetase]]
[[Category: pyrococcus horikoshii]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomics]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:36:00 2007''

Latest revision as of 23:57, 27 December 2023

Crystal structure of Alanyl-tRNA Synthetase from Pyrococcus horikoshii OT3

1v4p, resolution 1.45Å

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