3a2p: Difference between revisions
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< | ==Structure of 6-aminohexanoate cyclic dimer hydrolase== | ||
<StructureSection load='3a2p' size='340' side='right'caption='[[3a2p]], [[Resolution|resolution]] 1.90Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3a2p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Paenarthrobacter_ureafaciens Paenarthrobacter ureafaciens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3A2P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3A2P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3a2p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3a2p OCA], [https://pdbe.org/3a2p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3a2p RCSB], [https://www.ebi.ac.uk/pdbsum/3a2p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3a2p ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NYLA_FLASK NYLA_FLASK] Specifically catalyzes the hydrolysis of 6-aminohexanoic acid cyclic dimer (1,8-diazacyclotetradecane-2,9-dione) to form the linear dimer 6-aminohexanoyl-6-aminohexanoic acid. Is inactive on 6-aminohexanoic acid oligomers (degree of polymerization 2 to 6), various other cyclic amides, cyclic diamides, linear amides, oligopeptides, and casein. Allows the bacterium to grow on a medium containing 6-aminohexanoic acid cyclic dimer as the sole carbon and nitrogen sources.<ref>PMID:923591</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/a2/3a2p_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3a2p ConSurf]. | |||
<div style="clear:both"></div> | |||
=== | ==See Also== | ||
*[[6-aminohexanoate-dimer hydrolase 3D structures|6-aminohexanoate-dimer hydrolase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Paenarthrobacter ureafaciens]] | |||
[[Category: Shibata N]] | |||
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