3la3: Difference between revisions
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New page: '''Unreleased structure''' The entry 3la3 is ON HOLD Authors: Zhao, M.X., JIang, Y.L., He, Y.X., Chen, Y.F., Teng, Y.B., Chen, Y.X., Zhang, C.C., Zhou, C.Z Description: Crystal structu... |
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==Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid== | |||
<StructureSection load='3la3' size='340' side='right'caption='[[3la3]], [[Resolution|resolution]] 2.40Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3la3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Nostoc_sp._PCC_7120_=_FACHB-418 Nostoc sp. PCC 7120 = FACHB-418]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LA3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LA3 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2FT:2,2-DIFLUOROPENTANEDIOIC+ACID'>2FT</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3la3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3la3 OCA], [https://pdbe.org/3la3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3la3 RCSB], [https://www.ebi.ac.uk/pdbsum/3la3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3la3 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/NTCA_NOSS1 NTCA_NOSS1] Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control. Has affinity for the xisA upstream region. Binds to a 66 bp region containing three repeats of the consensus recognition sequence 5'-ACATT-3'. | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/la/3la3_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3la3 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Nostoc sp. PCC 7120 = FACHB-418]] | |||
[[Category: Chen YF]] | |||
[[Category: Chen YX]] | |||
[[Category: He YX]] | |||
[[Category: Jiang YL]] | |||
[[Category: Teng YB]] | |||
[[Category: Zhang CC]] | |||
[[Category: Zhao MX]] | |||
[[Category: Zhou CZ]] | |||
Latest revision as of 08:30, 20 March 2024
Crystal structure of NtcA in complex with 2,2-difluoropentanedioic acid
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