1z82: Difference between revisions

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New page: left|200px<br /><applet load="1z82" size="450" color="white" frame="true" align="right" spinBox="true" caption="1z82, resolution 2.000Å" /> '''Crystal structure o...
 
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[[Image:1z82.gif|left|200px]]<br /><applet load="1z82" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1z82, resolution 2.000&Aring;" />
'''Crystal structure of glycerol-3-phosphate dehydrogenase (TM0378) from THERMOTOGA MARITIMA at 2.00 A resolution'''<br />


==About this Structure==
==Crystal structure of glycerol-3-phosphate dehydrogenase (TM0378) from THERMOTOGA MARITIMA at 2.00 A resolution==
1Z82 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Thermotoga_maritima_msb8 Thermotoga maritima msb8] with NDP, G3H, G3P, MRD and MPD as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Glycerol-3-phosphate_dehydrogenase_(NAD(+)) Glycerol-3-phosphate dehydrogenase (NAD(+))], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.8 1.1.1.8] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1Z82 OCA].
<StructureSection load='1z82' size='340' side='right'caption='[[1z82]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
[[Category: Glycerol-3-phosphate dehydrogenase (NAD(+))]]
== Structural highlights ==
[[Category: Single protein]]
<table><tr><td colspan='2'>[[1z82]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima_MSB8 Thermotoga maritima MSB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Z82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Z82 FirstGlance]. <br>
[[Category: Thermotoga maritima msb8]]
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
[[Category: JCSG, Joint.Center.for.Structural.Genomics.]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=G3H:GLYCERALDEHYDE-3-PHOSPHATE'>G3H</scene>, <scene name='pdbligand=G3P:SN-GLYCEROL-3-PHOSPHATE'>G3P</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene></td></tr>
[[Category: G3H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1z82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1z82 OCA], [https://pdbe.org/1z82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1z82 RCSB], [https://www.ebi.ac.uk/pdbsum/1z82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1z82 ProSAT], [https://www.topsan.org/Proteins/JCSG/1z82 TOPSAN]</span></td></tr>
[[Category: G3P]]
</table>
[[Category: MPD]]
== Function ==
[[Category: MRD]]
[https://www.uniprot.org/uniprot/GPDA_THESQ GPDA_THESQ] Catalyzes the reduction of the glycolytic intermediate dihydroxyacetone phosphate (DHAP) to sn-glycerol 3-phosphate (G3P), the key precursor for phospholipid synthesis.[HAMAP-Rule:MF_00394]
[[Category: NDP]]
== Evolutionary Conservation ==
[[Category: glycerol-3-phosphate dehydrogenase]]
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: jcsg]]
Check<jmol>
[[Category: joint center for structural genomics]]
  <jmolCheckbox>
[[Category: protein structure initiative]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z8/1z82_consurf.spt"</scriptWhenChecked>
[[Category: psi]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: structural genomics]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: tm0378]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1z82 ConSurf].
<div style="clear:both"></div>


''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:46:47 2007''
==See Also==
*[[Glycerol-3-phosphate dehydrogenase 3D structures|Glycerol-3-phosphate dehydrogenase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermotoga maritima MSB8]]

Latest revision as of 07:44, 30 October 2024

Crystal structure of glycerol-3-phosphate dehydrogenase (TM0378) from THERMOTOGA MARITIMA at 2.00 A resolution

1z82, resolution 2.00Å

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