1zc2: Difference between revisions

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New page: left|200px<br /><applet load="1zc2" size="450" color="white" frame="true" align="right" spinBox="true" caption="1zc2, resolution 2.09Å" /> '''Crystal Structure of...
 
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[[Image:1zc2.gif|left|200px]]<br /><applet load="1zc2" size="450" color="white" frame="true" align="right" spinBox="true"
caption="1zc2, resolution 2.09&Aring;" />
'''Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule'''<br />


==About this Structure==
==Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule==
1ZC2 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae] with CIT as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1ZC2 OCA].  
<StructureSection load='1zc2' size='340' side='right'caption='[[1zc2]], [[Resolution|resolution]] 2.09&Aring;' scene=''>
[[Category: Beta-lactamase]]
== Structural highlights ==
<table><tr><td colspan='2'>[[1zc2]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ZC2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ZC2 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1zc2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1zc2 OCA], [https://pdbe.org/1zc2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1zc2 RCSB], [https://www.ebi.ac.uk/pdbsum/1zc2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1zc2 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q48434_KLEPN Q48434_KLEPN]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zc/1zc2_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1zc2 ConSurf].
<div style="clear:both"></div>
 
==See Also==
*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
__TOC__
</StructureSection>
[[Category: Klebsiella pneumoniae]]
[[Category: Klebsiella pneumoniae]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Bauvois, C.]]
[[Category: Bauvois C]]
[[Category: Ferrer, J.L.]]
[[Category: Ferrer J-L]]
[[Category: Fieulaine, S.]]
[[Category: Fieulaine S]]
[[Category: Frere, J.M.]]
[[Category: Frere J-M]]
[[Category: Galleni, M.]]
[[Category: Galleni M]]
[[Category: Jacquamet, L.]]
[[Category: Jacquamet L]]
[[Category: CIT]]
[[Category: ampc-type]]
[[Category: beta-lactamase cephalosporinase]]
[[Category: citrate]]
[[Category: serine hydrolase]]
 
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Sun Nov 25 04:49:01 2007''

Latest revision as of 13:39, 13 March 2024

Crystal Structure of plasmid-encoded class C beta-lactamase CMY-2 complexed with citrate molecule

1zc2, resolution 2.09Å

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