3ae2: Difference between revisions
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New page: '''Unreleased structure''' The entry 3ae2 is ON HOLD Authors: Harada, S., Sasaki, T., Shindo, M., Kido, Y., Inaoka, D. K., Omori, J., Osanai, A., Sakamoto, K., Mao, J., Matsuoka, S., In... |
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==Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide== | |||
<StructureSection load='3ae2' size='340' side='right'caption='[[3ae2]], [[Resolution|resolution]] 3.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3ae2]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3AE2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3AE2 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPH:L-ALPHA-PHOSPHATIDYL-BETA-OLEOYL-GAMMA-PALMITOYL-PHOSPHATIDYLETHANOLAMINE'>EPH</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=FES:FE2/S2+(INORGANIC)+CLUSTER'>FES</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=MLI:MALONATE+ION'>MLI</scene>, <scene name='pdbligand=SLI:2-HYDROXY-N-PHENYLBENZAMIDE'>SLI</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ae2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ae2 OCA], [https://pdbe.org/3ae2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ae2 RCSB], [https://www.ebi.ac.uk/pdbsum/3ae2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ae2 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/SDHA_PIG SDHA_PIG] Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). Can act as a tumor suppressor (By similarity). | |||
==See Also== | |||
*[[Succinate dehydrogenase 3D structures|Succinate dehydrogenase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Sus scrofa]] | |||
[[Category: Harada S]] | |||
[[Category: Honma T]] | |||
[[Category: Inaoka DK]] | |||
[[Category: Inoue M]] | |||
[[Category: Kido Y]] | |||
[[Category: Kita K]] | |||
[[Category: Mao J]] | |||
[[Category: Matsuoka S]] | |||
[[Category: Omori J]] | |||
[[Category: Osanai A]] | |||
[[Category: Sakamoto K]] | |||
[[Category: Sasaki T]] | |||
[[Category: Shindo M]] | |||
[[Category: Tanaka A]] | |||
Latest revision as of 08:49, 13 August 2026
Crystal structure of porcine heart mitochondrial complex II bound with 2-Hydroxy-N-phenyl-benzamide
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