3kz3: Difference between revisions

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{{Seed}}
[[Image:3kz3.jpg|left|200px]]


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==A structure of a lambda repressor fragment mutant==
The line below this paragraph, containing "STRUCTURE_3kz3", creates the "Structure Box" on the page.
<StructureSection load='3kz3' size='340' side='right'caption='[[3kz3]], [[Resolution|resolution]] 1.64&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3kz3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_Lambda Escherichia virus Lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KZ3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.64&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kz3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kz3 OCA], [https://pdbe.org/3kz3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kz3 RCSB], [https://www.ebi.ac.uk/pdbsum/3kz3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kz3 ProSAT]</span></td></tr>
{{STRUCTURE_3kz3|  PDB=3kz3  |  SCENE=  }}
</table>
 
== Function ==
===A structure of a lambda repressor fragment mutant===
[https://www.uniprot.org/uniprot/RPC1_LAMBD RPC1_LAMBD] Repressor protein CI allows phage lambda to reside inactively in the chromosome of its host bacterium. This lysogenic state is maintained by binding of regulatory protein CI to the OR and OL operators, preventing transcription of proteins necessary for lytic development.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_20138892}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 20138892 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kz/3kz3_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_20138892}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3kz3 ConSurf].
3KZ3 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Enterobacteria_phage_lambda Enterobacteria phage lambda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KZ3 OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:20138892</ref><references group="xtra"/>
[[Category: Escherichia virus Lambda]]
[[Category: Enterobacteria phage lambda]]
[[Category: Large Structures]]
[[Category: Gao, Y.]]
[[Category: Gao Y]]
[[Category: Gruebele, M.]]
[[Category: Gruebele M]]
[[Category: Liu, F.]]
[[Category: Liu F]]
[[Category: Dna-binding]]
[[Category: Five helix bundle]]
[[Category: Repressor]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:32:12 2010''