2zza: Difference between revisions

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{{Seed}}
[[Image:2zza.jpg|left|200px]]


<!--
==Moritella profunda Dihydrofolate reductase complex with NADP+ and Folate==
The line below this paragraph, containing "STRUCTURE_2zza", creates the "Structure Box" on the page.
<StructureSection load='2zza' size='340' side='right'caption='[[2zza]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2zza]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Moritella_profunda Moritella profunda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZZA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=FOL:FOLIC+ACID'>FOL</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene></td></tr>
{{STRUCTURE_2zza| PDB=2zza |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zza FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zza OCA], [https://pdbe.org/2zza PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zza RCSB], [https://www.ebi.ac.uk/pdbsum/2zza PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zza ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q70YQ6_MORPR Q70YQ6_MORPR] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis (By similarity).[PIRNR:PIRNR000194]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zz/2zza_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zza ConSurf].
<div style="clear:both"></div>


===Moritella profunda Dihydrofolate reductase complex with NADP+ and Folate===
==See Also==
 
*[[Dihydrofolate reductase 3D structures|Dihydrofolate reductase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
2ZZA is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Moritella_profunda Moritella profunda]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZZA OCA].
[[Category: Large Structures]]
[[Category: Dihydrofolate reductase]]
[[Category: Moritella profunda]]
[[Category: Akasaka, K.]]
[[Category: Gekko, K.]]
[[Category: Hata, K.]]
[[Category: Murakami, C.]]
[[Category: Ohmae, E.]]
[[Category: Shiro, Y.]]
[[Category: Tanaka, T.]]
[[Category: Deep-sea]]
[[Category: Dihydrofolate reductase]]
[[Category: Folic acid]]
[[Category: High pressure]]
[[Category: Low temperature]]
[[Category: Moritella profunda]]
[[Category: Moritella profunda]]
[[Category: Nadp]]
[[Category: Akasaka K]]
[[Category: Oxidoreductase]]
[[Category: Gekko K]]
[[Category: Piezophilic]]
[[Category: Hata K]]
[[Category: Psychrophilic]]
[[Category: Murakami C]]
[[Category: Psychropiezophilic]]
[[Category: Ohmae E]]
 
[[Category: Shiro Y]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 25 13:55:31 2010''
[[Category: Tanaka T]]
Retrieved from "https://proteopedia.org/2zza"