3m0i: Difference between revisions
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New page: '''Unreleased structure''' The entry 3m0i is ON HOLD Authors: Koch, C., Heine, A., Klebe, G. Description: Human Aldose Reductase mutant T113V in complex with Zopolrestat ''Page seeded... |
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==Human Aldose Reductase mutant T113V in complex with Zopolrestat== | |||
<StructureSection load='3m0i' size='340' side='right'caption='[[3m0i]], [[Resolution|resolution]] 1.07Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3m0i]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M0I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M0I FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.07Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=ZST:3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE+ACETIC+ACID'>ZST</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m0i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m0i OCA], [https://pdbe.org/3m0i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m0i RCSB], [https://www.ebi.ac.uk/pdbsum/3m0i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m0i ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | |||
==See Also== | |||
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Heine A]] | |||
[[Category: Klebe G]] | |||
[[Category: Koch C]] | |||
Latest revision as of 08:47, 7 February 2024
Human Aldose Reductase mutant T113V in complex with Zopolrestat
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