3l5k: Difference between revisions

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{{Seed}}
[[Image:3l5k.jpg|left|200px]]


<!--
==The crystal structure of human Haloacid Dehalogenase-like Hydrolase Domain containing 1A (HDHD1A)==
The line below this paragraph, containing "STRUCTURE_3l5k", creates the "Structure Box" on the page.
<StructureSection load='3l5k' size='340' side='right'caption='[[3l5k]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3l5k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3L5K FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
{{STRUCTURE_3l5k|  PDB=3l5k  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3l5k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3l5k OCA], [https://pdbe.org/3l5k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3l5k RCSB], [https://www.ebi.ac.uk/pdbsum/3l5k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3l5k ProSAT]</span></td></tr>
 
</table>
===The crystal structure of human Haloacid Dehalogenase-like Hydrolase Domain containing 1A (HDHD1A)===
== Function ==
 
[https://www.uniprot.org/uniprot/HDHD1_HUMAN HDHD1_HUMAN] Dephosphorylates pseudouridine 5'-phosphate, a potential intermediate in rRNA degradation. Pseudouridine is then excreted intact in urine.<ref>PMID:20722631</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3L5K is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3L5K OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/l5/3l5k_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3l5k ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Allerston, C.]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H.]]
[[Category: Allerston C]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Delft, F von.]]
[[Category: Bountra C]]
[[Category: Edwards, A.]]
[[Category: Edwards A]]
[[Category: Guo, K.]]
[[Category: Guo K]]
[[Category: Kavanagh, K L.]]
[[Category: Kavanagh KL]]
[[Category: Muniz, J.]]
[[Category: Muniz J]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: Picaud, S.]]
[[Category: Picaud S]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Ugochukwu E]]
[[Category: Ugochukwu, E.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Yue WW]]
[[Category: Yue, W W.]]
[[Category: Von Delft F]]
[[Category: Haloacid dehalogenase-like hydrolase domain containing 1a]]
[[Category: Hdhd1a]]
[[Category: Hydrolase]]
[[Category: Polymorphism]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Mar 10 14:40:22 2010''
Retrieved from "https://proteopedia.org/3l5k"