2kvg: Difference between revisions
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==Structure of the three-Cys2His2 domain of mouse testis zinc finger protein== | |||
<StructureSection load='2kvg' size='340' side='right'caption='[[2kvg]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2kvg]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KVG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KVG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kvg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kvg OCA], [https://pdbe.org/2kvg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kvg RCSB], [https://www.ebi.ac.uk/pdbsum/2kvg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kvg ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/ZBT32_MOUSE ZBT32_MOUSE] DNA-binding protein that binds to the to a 5'-TGTACAGTGT-3' core sequence. May function as a transcriptional transactivator and transcriptional repressor (By similarity). Probably exerts its repressor effect by preventing GATA3 from binding to DNA. May play a role in regulating the differentiation and activation of helper T-cells.<ref>PMID:11279021</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Chen C]] | |||
[[Category: Chou C-C]] | |||
[[Category: Lou Y-C]] | |||
Latest revision as of 06:49, 1 May 2024
Structure of the three-Cys2His2 domain of mouse testis zinc finger protein
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