2a12: Difference between revisions

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{{Theoretical_model}}
{{Theoretical_model}}
{{Seed}}
[[Image:2a12.png|left|200px]]


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==THEORETICAL MODEL OF THE AI5G GROUP II INTRON==
The line below this paragraph, containing "STRUCTURE_2a12", creates the "Structure Box" on the page.
<StructureSection load='2a12' size='340' side='right'caption='[[2a12]]' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2A12 FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2a12 FirstGlance], [https://www.ebi.ac.uk/pdbsum/2a12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2a12 ProSAT]</span></td></tr>
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</table>
{{STRUCTURE_2a12|  PDB=2a12  |  SCENE=  }}
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== Publication Abstract from PubMed ==
Despite the biological importance of self-splicing group II introns, little is known about their structural organization. Synthetic incorporation of site-specific photo-cross-linkers within catalytic domains resulted in functional distance constraints that, when combined with known tertiary interactions, provide a three-dimensional view of the active intron architecture. All functionalities important for both steps of splicing are proximal before the first step, suggestive of a single active-site region for group II intron catalysis.


===THEORETICAL MODEL OF THE AI5G GROUP II INTRON===
A single active-site region for a group II intron.,de Lencastre A, Hamill S, Pyle AM Nat Struct Mol Biol. 2005 Jul;12(7):626-7. Epub 2005 Jun 26. PMID:15980867<ref>PMID:15980867</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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(as it appears on PubMed at http://www.pubmed.gov), where 15980867 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_15980867}}
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</StructureSection>
==About this Structure==
[[Category: Theoretical Model]]
Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A12 OCA].
[[Category: Large Structures]]
 
==Reference==
<ref group="xtra">PMID:15980867</ref><references group="xtra"/>
[[Category: De Lencastre, A]]
[[Category: De Lencastre, A]]
[[Category: Hamill, S]]
[[Category: Hamill, S]]
[[Category: Pyle, A M]]
[[Category: Pyle, A M]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr  8 08:59:14 2010''