3let: Difference between revisions

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{{Seed}}
[[Image:3let.jpg|left|200px]]


<!--
==Crystal Structure of Fic domain containing AMPylator, VopS==
The line below this paragraph, containing "STRUCTURE_3let", creates the "Structure Box" on the page.
<StructureSection load='3let' size='340' side='right'caption='[[3let]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3let]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_parahaemolyticus Vibrio parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LET OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LET FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.802&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3let FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3let OCA], [https://pdbe.org/3let PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3let RCSB], [https://www.ebi.ac.uk/pdbsum/3let PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3let ProSAT]</span></td></tr>
{{STRUCTURE_3let|  PDB=3let  |  SCENE=  }}
</table>
 
== Function ==
===Crystal Structure of Fic domain containing AMPylator, VopS===
[https://www.uniprot.org/uniprot/VOPS_VIBPA VOPS_VIBPA] Adenylyltransferase involved in virulence by mediating the addition of adenosine 5'-monophosphate (AMP) to specific threonine residue of host Rho GTPases RhoA, Rac and Cdc42. The resulting AMPylation prevents the interaction of Rho GTPases with downstream effectors, thereby inhibiting actin assembly in infected cells.<ref>PMID:19039103</ref> <ref>PMID:20410310</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
3LET is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Vibrio_parahaemolyticus Vibrio parahaemolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LET OCA].  
</StructureSection>
[[Category: Nicotinamide-nucleotide adenylyltransferase]]
[[Category: Large Structures]]
[[Category: Vibrio parahaemolyticus]]
[[Category: Vibrio parahaemolyticus]]
[[Category: Brautigam, C A.]]
[[Category: Brautigam CA]]
[[Category: Grishin, N V.]]
[[Category: Grishin NV]]
[[Category: Kinch, L N.]]
[[Category: Kinch LN]]
[[Category: Luong, P H.]]
[[Category: Luong PH]]
[[Category: Orth, K.]]
[[Category: Orth K]]
[[Category: Tomchick, D R.]]
[[Category: Tomchick DR]]
[[Category: Ampylation]]
[[Category: Effector]]
[[Category: Fic domain]]
[[Category: Nucleotidyltransferase]]
[[Category: T3ss]]
[[Category: Transferase]]
[[Category: Type iii]]
[[Category: Vibrio]]
[[Category: Virulence]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 21 11:05:21 2010''
Retrieved from "https://proteopedia.org/3let"