3mkl: Difference between revisions

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{{Seed}}
[[Image:3mkl.jpg|left|200px]]


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==Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12==
The line below this paragraph, containing "STRUCTURE_3mkl", creates the "Structure Box" on the page.
<StructureSection load='3mkl' size='340' side='right'caption='[[3mkl]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3mkl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MKL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
{{STRUCTURE_3mkl|  PDB=3mkl  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mkl OCA], [https://pdbe.org/3mkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mkl RCSB], [https://www.ebi.ac.uk/pdbsum/3mkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mkl ProSAT]</span></td></tr>
 
</table>
===Crystal structure of DNA-binding transcriptional dual regulator from Escherichia coli K-12===
== Function ==
 
[https://www.uniprot.org/uniprot/GADX_ECOLI GADX_ECOLI] Positively regulates the expression of about fifteen genes involved in acid resistance such as gadA, gadB and gadC. Depending on the conditions (growth phase and medium), can repress gadW.<ref>PMID:11298273</ref> <ref>PMID:11976288</ref> <ref>PMID:12446650</ref> <ref>PMID:12730179</ref> <ref>PMID:14617649</ref> <ref>PMID:14702398</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3MKL is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MKL OCA].  
Check<jmol>
[[Category: Escherichia coli]]
  <jmolCheckbox>
[[Category: Chang, C.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mk/3mkl_consurf.spt"</scriptWhenChecked>
[[Category: Clancy, S.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Joachimiak, A.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: MCSG, Midwest Center for Structural Genomics.]]
  </jmolCheckbox>
[[Category: Mack, J.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mkl ConSurf].
[[Category: Dna-binding protein]]
<div style="clear:both"></div>
[[Category: Mcsg]]
== References ==
[[Category: Midwest center for structural genomic]]
<references/>
[[Category: Protein structure initiative]]
__TOC__
[[Category: Psi2]]
</StructureSection>
[[Category: Structural genomic]]
[[Category: Escherichia coli K-12]]
[[Category: Transcription regulator]]
[[Category: Large Structures]]
[[Category: Transcriptional dual regulator]]
[[Category: Chang C]]
 
[[Category: Clancy S]]
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 28 11:12:06 2010''
[[Category: Joachimiak A]]
[[Category: Mack J]]