3ney: Difference between revisions

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'''Unreleased structure'''


The entry 3ney is ON HOLD  until Aug 03 2011
==Crystal structure of the kinase domain of MPP1/p55==
 
<StructureSection load='3ney' size='340' side='right'caption='[[3ney]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
Authors: Shen, Y., Tong, Y., Zhong, N., Guan, X., Tempel, W., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H., Structural Genomics Consortium (SGC)
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3ney]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NEY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NEY FirstGlance]. <br>
Description: Crystal structure of the kinase domain of MPP1/p55 (CASP Target)
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.26&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:42:52 2010''
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ney FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ney OCA], [https://pdbe.org/3ney PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ney RCSB], [https://www.ebi.ac.uk/pdbsum/3ney PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ney ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/EM55_HUMAN EM55_HUMAN] Essential regulator of neutrophil polarity. Regulates neutrophil polarization by regulating AKT1 phosphorylation through a mechanism that is independent of PIK3CG activity (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/3ney_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ney ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev A]]
[[Category: Bountra C]]
[[Category: Edwards AM]]
[[Category: Guan X]]
[[Category: MacKenzie F]]
[[Category: Park H]]
[[Category: Shen Y]]
[[Category: Tempel W]]
[[Category: Tong Y]]
[[Category: Weigelt J]]
[[Category: Zhong N]]
Retrieved from "https://proteopedia.org/3ney"