3lzc: Difference between revisions

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{{Seed}}
[[Image:3lzc.jpg|left|200px]]


<!--
==Crystal structure of Dph2 from Pyrococcus horikoshii==
The line below this paragraph, containing "STRUCTURE_3lzc", creates the "Structure Box" on the page.
<StructureSection load='3lzc' size='340' side='right'caption='[[3lzc]], [[Resolution|resolution]] 2.26&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lzc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LZC FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.261&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lzc OCA], [https://pdbe.org/3lzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lzc RCSB], [https://www.ebi.ac.uk/pdbsum/3lzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lzc ProSAT]</span></td></tr>
{{STRUCTURE_3lzc|  PDB=3lzc  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of Dph2 from Pyrococcus horikoshii===
[https://www.uniprot.org/uniprot/DPH2_PYRHO DPH2_PYRHO] Catalyzes the first step of diphthamide biosynthesis, i.e. the transfer of the 3-amino-3-carboxypropyl group from S-adenosyl-L-methionine (SAM) to the C2 position of the imidazole ring of the target histidine residue in translation elongation factor 2 (EF-2).<ref>PMID:20559380</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
3LZC is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Pyrococcus_horikoshii Pyrococcus horikoshii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LZC OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/lz/3lzc_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lzc ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Pyrococcus horikoshii]]
[[Category: Pyrococcus horikoshii]]
[[Category: Dzikovski, B.]]
[[Category: Dzikovski B]]
[[Category: Ealick, S E.]]
[[Category: Ealick SE]]
[[Category: Freed, J.]]
[[Category: Freed J]]
[[Category: Koralewski, R M.]]
[[Category: Koralewski RM]]
[[Category: Krebs, C.]]
[[Category: Krebs C]]
[[Category: Lee, M.]]
[[Category: Lee M]]
[[Category: Lin, H.]]
[[Category: Lin H]]
[[Category: Torelli, A T.]]
[[Category: Torelli AT]]
[[Category: Wang, E.]]
[[Category: Wang E]]
[[Category: Zhang, Y.]]
[[Category: Zhang Y]]
[[Category: Zhu, X.]]
[[Category: Zhu X]]
[[Category: Biosynthetic protein]]
[[Category: Diphthamide biosynthesis]]
[[Category: Gene triplication]]
[[Category: Radical sam enzyme]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 23 08:50:27 2010''
Retrieved from "https://proteopedia.org/3lzc"