3i1f: Difference between revisions

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{{Seed}}
[[Image:3i1f.jpg|left|200px]]


<!--
==Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p==
The line below this paragraph, containing "STRUCTURE_3i1f", creates the "Structure Box" on the page.
<StructureSection load='3i1f' size='340' side='right'caption='[[3i1f]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3i1f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3I1F FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GCP:PHOSPHOMETHYLPHOSPHONIC+ACID+GUANYLATE+ESTER'>GCP</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3i1f|  PDB=3i1f  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3i1f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3i1f OCA], [https://pdbe.org/3i1f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3i1f RCSB], [https://www.ebi.ac.uk/pdbsum/3i1f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3i1f ProSAT]</span></td></tr>
 
</table>
===Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p===
== Function ==
 
[https://www.uniprot.org/uniprot/IF2G_SACS2 IF2G_SACS2] eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA.[HAMAP-Rule:MF_00119]
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
3I1F is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Sulfolobus_solfataricus Sulfolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3I1F OCA].  
Check<jmol>
[[Category: Sulfolobus solfataricus]]
  <jmolCheckbox>
[[Category: Blaesi, U.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i1/3i1f_consurf.spt"</scriptWhenChecked>
[[Category: Garber, M B.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
[[Category: Nikonov, O S.]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Nikonov, S V.]]
  </jmolCheckbox>
[[Category: Nikulin, A D.]]
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3i1f ConSurf].
[[Category: Stolboushkina, E A.]]
<div style="clear:both"></div>
[[Category: Aif2]]
__TOC__
[[Category: Gdpcp]]
</StructureSection>
[[Category: Gtp-binding]]
[[Category: Large Structures]]
[[Category: Initiation factor]]
[[Category: Saccharolobus solfataricus]]
[[Category: Initiation factor 2 gamma subunit]]
[[Category: Blaesi U]]
[[Category: Initiation of the translation]]
[[Category: Garber MB]]
[[Category: Mrna binding]]
[[Category: Nikonov OS]]
[[Category: Nucleotide binding]]
[[Category: Nikonov SV]]
[[Category: Nucleotide-binding]]
[[Category: Nikulin AD]]
[[Category: Protein biosynthesis]]
[[Category: Stolboushkina EA]]
[[Category: Translation]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jun 30 13:46:21 2010''

Latest revision as of 09:15, 30 October 2024

Gamma-subunit of the translation initiation factor 2 from S. solfataricus in complex with Gpp(CH2)p

3i1f, resolution 2.50Å

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