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{{Seed}}
[[Image:3k52.png|left|200px]]


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==Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP==
The line below this paragraph, containing "STRUCTURE_3k52", creates the "Structure Box" on the page.
<StructureSection load='3k52' size='340' side='right'caption='[[3k52]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3k52]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K52 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3K52 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IP8:ISOPENTENYL+PHOSPHATE'>IP8</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3k52|  PDB=3k52  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3k52 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3k52 OCA], [https://pdbe.org/3k52 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3k52 RCSB], [https://www.ebi.ac.uk/pdbsum/3k52 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3k52 ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP===
== Function ==
 
[https://www.uniprot.org/uniprot/IPK_METJA IPK_METJA] Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids. Has no activity with farnesyl phosphate.<ref>PMID:16621811</ref> <ref>PMID:20392112</ref>  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_20392112}}, adds the Publication Abstract to the page
Check<jmol>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k5/3k52_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_20392112}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3K52 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Methanocaldococcus_jannaschii Methanocaldococcus jannaschii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3K52 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3k52 ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:20392112</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Dellas, N.]]
[[Category: Dellas N]]
[[Category: Noel, J P.]]
[[Category: Noel JP]]
[[Category: Archaea]]
[[Category: Atp-binding]]
[[Category: Isopentenyl diphosphate]]
[[Category: Isopentenyl monophosphate]]
[[Category: Isoprenoid biosynthesis]]
[[Category: Methanocaldococcus jannaschii]]
[[Category: Mevalonate pathway]]
[[Category: Small molecule kinase]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  7 07:52:06 2010''

Latest revision as of 10:15, 21 February 2024

Crystal Structure of Isopentenyl Phosphate Kinase from M. jannaschii in complex with IP

3k52, resolution 2.70Å

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