3m8r: Difference between revisions

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{{Seed}}
[[Image:3m8r.jpg|left|200px]]


<!--
==Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-ethylated dTTP==
The line below this paragraph, containing "STRUCTURE_3m8r", creates the "Structure Box" on the page.
<StructureSection load='3m8r' size='340' side='right'caption='[[3m8r]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3m8r]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M8R FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=15P:POLYETHYLENE+GLYCOL+(N=34)'>15P</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=DOC:2,3-DIDEOXYCYTIDINE-5-MONOPHOSPHATE'>DOC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HXZ:4-ETHYLTHYMIDINE+5-(TETRAHYDROGEN+TRIPHOSPHATE)'>HXZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3m8r| PDB=3m8r |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m8r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m8r OCA], [https://pdbe.org/3m8r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m8r RCSB], [https://www.ebi.ac.uk/pdbsum/3m8r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m8r ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DPO1_THEAQ DPO1_THEAQ]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/m8/3m8r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3m8r ConSurf].
<div style="clear:both"></div>


===Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-ethylated dTTP===
==See Also==
 
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3M8R is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Thermus_aquaticus Thermus aquaticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M8R OCA].
[[Category: Large Structures]]
 
==Reference==
<ref group="xtra">PMID:20572212</ref><references group="xtra"/>
[[Category: DNA-directed DNA polymerase]]
[[Category: Thermus aquaticus]]
[[Category: Thermus aquaticus]]
[[Category: Betz, K.]]
[[Category: Betz K]]
[[Category: Diederichs, K.]]
[[Category: Diederichs K]]
[[Category: Marx, A.]]
[[Category: Marx A]]
[[Category: Artificial nucleotide]]
[[Category: Dna]]
[[Category: Dna polymerase]]
[[Category: Dna replication]]
[[Category: Dna-binding]]
[[Category: Dna-directed dna polymerase]]
[[Category: Modified nucleotide]]
[[Category: Nucleotide probe]]
[[Category: Nucleotide]]
[[Category: Nucleotidyltransferase]]
[[Category: Transferase]]
[[Category: Transferase-dna complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul  7 08:42:24 2010''

Latest revision as of 08:49, 6 September 2023

Crystal structure of the large fragment of DNA polymerase I from Thermus aquaticus in a closed ternary complex with trapped 4'-ethylated dTTP

3m8r, resolution 2.00Å

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