2xik: Difference between revisions

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{{Seed}}
[[Image:2xik.jpg|left|200px]]


<!--
==Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1)==
The line below this paragraph, containing "STRUCTURE_2xik", creates the "Structure Box" on the page.
<StructureSection load='2xik' size='340' side='right'caption='[[2xik]], [[Resolution|resolution]] 1.97&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2xik]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.97&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=J60:5-[(E)-(5-CHLORO-2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]-N-[2-(DIETHYLAMINO)ETHYL]-2,4-DIMETHYL-1H-PYRROLE-3-CARBOXAMIDE'>J60</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
{{STRUCTURE_2xik| PDB=2xik |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xik FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xik OCA], [https://pdbe.org/2xik PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xik RCSB], [https://www.ebi.ac.uk/pdbsum/2xik PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xik ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/STK25_HUMAN STK25_HUMAN] Oxidant stress-activated serine/threonine kinase that may play a role in the response to environmental stress. Targets to the Golgi apparatus where it appears to regulate protein transport events, cell adhesion, and polarity complexes important for cell migration.<ref>PMID:15037601</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xi/2xik_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xik ConSurf].
<div style="clear:both"></div>


===STRUCTURE OF HUMAN YSK1 (YEAST SPS1-STE20-RELATED KINASE 1)===
==See Also==
 
*[[Serine/threonine protein kinase 3D structures|Serine/threonine protein kinase 3D structures]]
 
== References ==
==About this Structure==
<references/>
2XIK is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIK OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Large Structures]]
[[Category: Allerston, C.]]
[[Category: Allerston C]]
[[Category: Arrowsmith, C H.]]
[[Category: Arrowsmith CH]]
[[Category: Berridge, G.]]
[[Category: Berridge G]]
[[Category: Bountra, C.]]
[[Category: Bountra C]]
[[Category: Brenner, B.]]
[[Category: Brenner B]]
[[Category: Chaikuad, A.]]
[[Category: Chaikuad A]]
[[Category: Daga, N.]]
[[Category: Daga N]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Elkins, J M.]]
[[Category: Elkins JM]]
[[Category: Gileadi, O.]]
[[Category: Gileadi O]]
[[Category: Knapp, S.]]
[[Category: Knapp S]]
[[Category: Mahajan, P.]]
[[Category: Mahajan P]]
[[Category: Muniz, J R.C.]]
[[Category: Muniz JRC]]
[[Category: Rellos, P.]]
[[Category: Rellos P]]
[[Category: Savitsky, P.]]
[[Category: Savitsky P]]
[[Category: Shrestha, B.]]
[[Category: Shrestha B]]
[[Category: Ugochukwu, E.]]
[[Category: Ugochukwu E]]
[[Category: Vollmar, M.]]
[[Category: Vollmar M]]
[[Category: Vondelft, F.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Von Delft F]]
[[Category: Kinase1]]
[[Category: Transferase]]
[[Category: Ysk1]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:17:16 2010''

Latest revision as of 09:36, 6 November 2024

Structure of Human YSK1 (Yeast Sps1-Ste20-related Kinase 1)

2xik, resolution 1.97Å

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