3n8f: Difference between revisions

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{{Seed}}
[[Image:3n8f.jpg|left|200px]]


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==Crystal structure of the complex of goat lactoperoxidase with thiocyanate at 3.2 A resolution==
The line below this paragraph, containing "STRUCTURE_3n8f", creates the "Structure Box" on the page.
<StructureSection load='3n8f' size='340' side='right'caption='[[3n8f]], [[Resolution|resolution]] 3.25&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3n8f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N8F FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.25&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr>
{{STRUCTURE_3n8f| PDB=3n8f |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n8f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n8f OCA], [https://pdbe.org/3n8f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n8f RCSB], [https://www.ebi.ac.uk/pdbsum/3n8f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n8f ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n8/3n8f_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview03.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n8f ConSurf].
<div style="clear:both"></div>


===Crystal structure of the complex of goat lactoperoxidase with thiocyanate at 3.2 A resolution===
==See Also==
 
*[[Lactoperoxidase|Lactoperoxidase]]
 
== References ==
==About this Structure==
<references/>
3N8F is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N8F OCA].
__TOC__
</StructureSection>
[[Category: Capra hircus]]
[[Category: Capra hircus]]
[[Category: Peroxidase]]
[[Category: Large Structures]]
[[Category: Kaur, P.]]
[[Category: Kaur P]]
[[Category: Sharma, S.]]
[[Category: Sharma S]]
[[Category: Singh, A K.]]
[[Category: Singh AK]]
[[Category: Singh, R P.]]
[[Category: Singh RP]]
[[Category: Singh, T P.]]
[[Category: Singh TP]]
[[Category: Sinha, M.]]
[[Category: Sinha M]]
[[Category: Vikram, G.]]
[[Category: Vikram G]]
[[Category: Complex]]
[[Category: Lactoperoxidase]]
[[Category: Metal binding protein]]
[[Category: Milk protein]]
[[Category: Nitrate]]
[[Category: Oxidoreductase]]
[[Category: Thiocyanate]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Jul 14 16:22:57 2010''
Retrieved from "https://proteopedia.org/3n8f"