3lyf: Difference between revisions

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[[Image:3lyf.png|left|200px]]


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==Crystal Structure of the Rift Valley Fever Virus Nucleocapsid Protein==
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<StructureSection load='3lyf' size='340' side='right'caption='[[3lyf]], [[Resolution|resolution]] 1.93&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lyf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rift_Valley_fever_virus Rift Valley fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LYF FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.93&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
{{STRUCTURE_3lyf|  PDB=3lyf  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lyf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lyf OCA], [https://pdbe.org/3lyf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lyf RCSB], [https://www.ebi.ac.uk/pdbsum/3lyf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lyf ProSAT]</span></td></tr>
 
</table>
===Crystal Structure of the Rift Valley Fever Virus Nucleocapsid Protein===
== Function ==
 
[https://www.uniprot.org/uniprot/NCAP_RVFV NCAP_RVFV] Encapsidates the genomic RNA, protecting it from nucleases (Probable) (PubMed:20547879). Displays high affinity for single-stranded nucleic acid (PubMed:23129612). The encapsidated genomic RNA is termed the nucleocapsid (NC) or ribonucleoprotein (PubMed:20547879). The ribonucleoprotein has a non-helical structure (PubMed:20547879). Serves as template for viral transcription and replication (By similarity). After replication, the nucleocapsid is recruited to the host Golgi apparatus by glycoprotein Gn for packaging into virus particles (By similarity).[UniProtKB:P21700]<ref>PMID:20547879</ref> <ref>PMID:23129612</ref> <ref>PMID:34960686</ref>
 
== Evolutionary Conservation ==
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ly/3lyf_consurf.spt"</scriptWhenChecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3LYF is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Rift_valley_fever_virus Rift valley fever virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LYF OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3lyf ConSurf].
 
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==Reference==
== References ==
<ref group="xtra">PMID:20547879</ref><references group="xtra"/>
<references/>
[[Category: Rift valley fever virus]]
__TOC__
[[Category: Raymond, D D.]]
</StructureSection>
[[Category: Smith, J L.]]
[[Category: Large Structures]]
[[Category: N protein]]
[[Category: Rift Valley fever virus]]
[[Category: Nucleocapsid protein]]
[[Category: Raymond DD]]
[[Category: Ribonucleoprotein]]
[[Category: Smith JL]]
[[Category: Rift valley fever virus]]
[[Category: Viral nucleoprotein]]
[[Category: Viral protein]]
 
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