3nxc: Difference between revisions
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New page: '''Unreleased structure''' The entry 3nxc is ON HOLD Authors: Tonthat, Nam K., Schumacher, Maria A. Description: Molecular mechanism by which the Escherichia coli nucleoid occlusion fa... |
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==Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check== | |||
<StructureSection load='3nxc' size='340' side='right'caption='[[3nxc]], [[Resolution|resolution]] 2.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3nxc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NXC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NXC FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nxc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nxc OCA], [https://pdbe.org/3nxc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nxc RCSB], [https://www.ebi.ac.uk/pdbsum/3nxc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nxc ProSAT]</span></td></tr> | |||
'' | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/SLMA_ECOLI SLMA_ECOLI] Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.[HAMAP-Rule:MF_01839]<ref>PMID:15916962</ref> <ref>PMID:21113127</ref> <ref>PMID:21321206</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli K-12]] | |||
[[Category: Large Structures]] | |||
[[Category: Schumacher MA]] | |||
[[Category: Tonthat NK]] | |||
Latest revision as of 10:01, 14 February 2024
Molecular mechanism by which the Escherichia coli nucleoid occlusion factor, SlmA, keeps cytokinesis in check
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