3ne1: Difference between revisions

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{{Seed}}
[[Image:3ne1.jpg|left|200px]]


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==Mycobacterium tuberculosis Acyl Carrier Protein Synthase in complex with sulfate ion==
The line below this paragraph, containing "STRUCTURE_3ne1", creates the "Structure Box" on the page.
<StructureSection load='3ne1' size='340' side='right'caption='[[3ne1]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ne1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NE1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NE1 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.51&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3ne1| PDB=3ne1 |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ne1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ne1 OCA], [https://pdbe.org/3ne1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ne1 RCSB], [https://www.ebi.ac.uk/pdbsum/3ne1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ne1 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ACPS_MYCTU ACPS_MYCTU] Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ne/3ne1_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ne1 ConSurf].
<div style="clear:both"></div>


===Mycobacterium tuberculosis Acyl Carrier Protein Synthase adopts two different structural conformations: pH driven conformational changes of ACPS enzyme===
==See Also==
 
*[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
3NE1 is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NE1 OCA].
[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Gokulan, K.]]
[[Category: Gokulan K]]
[[Category: Acp]]
[[Category: Acyl carrier protein]]
[[Category: Acyl carrier protein synthase]]
[[Category: Fatty acid synthase]]
[[Category: Mycobacterium tuberculosis structural proteomics project]]
[[Category: Transferase]]
 
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Retrieved from "https://proteopedia.org/3ne1"