3lln: Difference between revisions

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{{Seed}}
[[Image:3lln.jpg|left|200px]]


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==Comparison between the orthorhombic an tetragonal form of the heptamer sequence d(GCG(xT)GCG)/d(CGCACGC).==
The line below this paragraph, containing "STRUCTURE_3lln", creates the "Structure Box" on the page.
<StructureSection load='3lln' size='340' side='right'caption='[[3lln]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3lln]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LLN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3LLN FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NCO:COBALT+HEXAMMINE(III)'>NCO</scene>, <scene name='pdbligand=XTR:[(1R,4S,6S)-6-HYDROXY-4-(5-METHYL-2,4-DIOXO-3,4-DIHYDROPYRIMIDIN-1(2H)-YL)CYCLOHEX-2-EN-1-YL]METHYL+DIHYDROGEN+PHOSPHATE'>XTR</scene></td></tr>
{{STRUCTURE_3lln|  PDB=3lln  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3lln FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3lln OCA], [https://pdbe.org/3lln PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3lln RCSB], [https://www.ebi.ac.uk/pdbsum/3lln PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3lln ProSAT]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Cyclohexene nucleic acid (CeNA) building blocks can be introduced into natural DNA sequences without a large conformational influence because of the ability of the six-membered sugar ring to mimic both the C2'-endo and C3'-endo conformations of the naturally occurring ribofuranose sugar ring. The non-self-complementary DNA sequence d[GCG(xT)GCG]/d(CGCACGC) with one incorporated CeNA (xT) moiety crystallizes in two forms: orthorhombic and tetragonal. The tetragonal form, which diffracts to 3 A resolution, is a kinetically stable polymorph of the orthorhombic form [Robeyns et al. (2010), Artificial DNA, 1, 1-7], which diffracts to 1.17 A resolution and is the thermodynamically stable form of the CeNA-incorporated duplex. Here, the two structures are compared, with special emphasis on the differences in crystal packing and the irreversible conversion of the kinetic form into the high-resolution diffracting thermodynamic form.


===Comparison between the orthorhombic an tetragonal form of the heptamer sequence d(GCG(xT)GCG)/d(CGCACGC).===
Comparison between the orthorhombic and tetragonal forms of the heptamer sequence d[GCG(xT)GCG]/d(CGCACGC).,Robeyns K, Herdewijn P, Van Meervelt L Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Sep 1;66(Pt, 9):1028-31. Epub 2010 Aug 26. PMID:20823518<ref>PMID:20823518</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
==About this Structure==
</div>
3LLN is a 2 chains structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3LLN OCA].
<div class="pdbe-citations 3lln" style="background-color:#fffaf0;"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:18198873</ref><ref group="xtra">PMID:18160414</ref><references group="xtra"/>
__TOC__
[[Category: Herdewijn, P.]]
</StructureSection>
[[Category: Meervelt, L Van.]]
[[Category: Large Structures]]
[[Category: Robeyns, K.]]
[[Category: Herdewijn P]]
[[Category: Cena]]
[[Category: Robeyns K]]
[[Category: Dna]]
[[Category: Van Meervelt L]]
[[Category: Double helix]]
[[Category: Right-handed]]
[[Category: Sugar modification]]
 
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Retrieved from "https://proteopedia.org/3lln"