2kre: Difference between revisions

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{{Seed}}
[[Image:2kre.png|left|200px]]


<!--
==Solution structure of E4B/UFD2A U-Box domain==
The line below this paragraph, containing "STRUCTURE_2kre", creates the "Structure Box" on the page.
<StructureSection load='2kre' size='340' side='right'caption='[[2kre]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2kre]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KRE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kre FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kre OCA], [https://pdbe.org/2kre PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kre RCSB], [https://www.ebi.ac.uk/pdbsum/2kre PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kre ProSAT]</span></td></tr>
{{STRUCTURE_2kre|  PDB=2kre  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of E4B/UFD2A U-Box domain===
[https://www.uniprot.org/uniprot/UBE4B_HUMAN UBE4B_HUMAN] Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity).
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_20696396}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 20696396 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2kre_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_20696396}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kre ConSurf].
2KRE is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KRE OCA].  
<div style="clear:both"></div>
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:20696396</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Botuyan, M.]]
[[Category: Large Structures]]
[[Category: Mer, G.]]
[[Category: Botuyan M]]
[[Category: Nomine, Y.]]
[[Category: Mer G]]
[[Category: Wasielewski, E.]]
[[Category: Nomine Y]]
[[Category: E3 ubiquitin ligase]]
[[Category: Wasielewski E]]
[[Category: E4 polyubiquitin chain elongation factor]]
[[Category: Phosphoprotein]]
[[Category: Protein binding]]
[[Category: U-box domain]]
[[Category: Ubl conjugation pathway]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Aug 25 08:18:12 2010''

Latest revision as of 06:48, 1 May 2024

Solution structure of E4B/UFD2A U-Box domain

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