3mh9: Difference between revisions

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{{Seed}}
[[Image:3mh9.jpg|left|200px]]


<!--
==Crystal structure of LprG mutant V91W from Mycobacterium tuberculosis==
The line below this paragraph, containing "STRUCTURE_3mh9", creates the "Structure Box" on the page.
<StructureSection load='3mh9' size='340' side='right'caption='[[3mh9]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3mh9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MH9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MH9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.794&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mh9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mh9 OCA], [https://pdbe.org/3mh9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mh9 RCSB], [https://www.ebi.ac.uk/pdbsum/3mh9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mh9 ProSAT]</span></td></tr>
{{STRUCTURE_3mh9|  PDB=3mh9  |  SCENE=  }}
</table>
 
== Function ==
===Crystal structure of LprG mutant V91W from Mycobacterium tuberculosis===
[https://www.uniprot.org/uniprot/LPRG_MYCTU LPRG_MYCTU] TLR2 agonist that can inhibit primary human macrophage MHC-II Ag processing. Required for Rv1410c (P55) activity.<ref>PMID:15294983</ref> <ref>PMID:18156250</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
<!--
Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_20694006}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 20694006 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mh/3mh9_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_20694006}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mh9 ConSurf].
3MH9 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MH9 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:20694006</ref><references group="xtra"/>
__TOC__
[[Category: Mycobacterium tuberculosis]]
</StructureSection>
[[Category: Sacchettini, J C.]]
[[Category: Large Structures]]
[[Category: TBSGC, TB Structural Genomics Consortium.]]
[[Category: Mycobacterium tuberculosis H37Rv]]
[[Category: Tsai, H C.]]
[[Category: Sacchettini JC]]
[[Category: Glycolipid binding protein]]
[[Category: Tsai H-C]]
[[Category: Lipid binding protein]]
[[Category: Lipoprotein]]
[[Category: Mutant lprg]]
[[Category: Structural genomic]]
[[Category: Tb structural genomics consortium]]
[[Category: Tbsgc]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep  1 09:48:51 2010''

Latest revision as of 10:25, 21 February 2024

Crystal structure of LprG mutant V91W from Mycobacterium tuberculosis

3mh9, resolution 1.79Å

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