3nto: Difference between revisions

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{{Seed}}
[[Image:3nto.jpg|left|200px]]


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==Crystal structure of K97V mutant myo-inositol dehydrogenase from Bacillus subtilis==
The line below this paragraph, containing "STRUCTURE_3nto", creates the "Structure Box" on the page.
<StructureSection load='3nto' size='340' side='right'caption='[[3nto]], [[Resolution|resolution]] 1.91&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3nto]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NTO FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9124&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr>
{{STRUCTURE_3nto|  PDB=3nto  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nto OCA], [https://pdbe.org/3nto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nto RCSB], [https://www.ebi.ac.uk/pdbsum/3nto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nto ProSAT]</span></td></tr>
 
</table>
===Crystal structure of K97V mutant myo-inositol dehydrogenase from Bacillus subtilis===
== Function ==
 
[https://www.uniprot.org/uniprot/IOLG_BACSU IOLG_BACSU] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively. Can also use D-glucose and D-xylose, and shows a trace of activity with D-ribose and D-fructose.<ref>PMID:112095</ref> <ref>PMID:16461681</ref>  
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/3nto_consurf.spt"</scriptWhenChecked>
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    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3NTO is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTO OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nto ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:20809899</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Inositol 2-dehydrogenase]]
[[Category: Large Structures]]
[[Category: Palmer, D R.J.]]
[[Category: Palmer DRJ]]
[[Category: Sanders, D A.R.]]
[[Category: Sanders DAR]]
[[Category: Straaten, K E.Van.]]
[[Category: Van Straaten KE]]
[[Category: Bsidh]]
[[Category: Glyceraldehyde-3-phosphate like c-terminal domain]]
[[Category: K97v mutant]]
[[Category: N-terminal rossmann fold domain]]
[[Category: Oxidoreductase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 15 10:52:40 2010''

Latest revision as of 06:42, 3 April 2024

Crystal structure of K97V mutant myo-inositol dehydrogenase from Bacillus subtilis

3nto, resolution 1.91Å

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