2k98: Difference between revisions

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{{Seed}}
[[Image:2k98.png|left|200px]]


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==Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle==
The line below this paragraph, containing "STRUCTURE_2k98", creates the "Structure Box" on the page.
<StructureSection load='2k98' size='340' side='right'caption='[[2k98]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
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<table><tr><td colspan='2'>[[2k98]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K98 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k98 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k98 OCA], [https://pdbe.org/2k98 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k98 RCSB], [https://www.ebi.ac.uk/pdbsum/2k98 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k98 ProSAT]</span></td></tr>
{{STRUCTURE_2k98|  PDB=2k98  |  SCENE=  }}
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Essential understanding: Elucidation of structural requirements and interactions of antimicrobial peptides with lipopolysaccharide (LPS) are essential to understand the mechanism of action of antimicrobial peptides. The highly active antimicrobial peptide MSI-594 (see figure for electrostatic potential surface) acquires a novel helical hairpin structure in complex with LPS. The structure and interactions of MSI-594 with LPS presented here provide important insights into the mechanism of outer membrane permeabilization by antimicrobial peptides.


===Helical hairpin structure of potent antimicrobial peptide MSI-594 in the presence of Lipopolysaccharide micelle===
Helical Hairpin Structure of a Potent Antimicrobial Peptide MSI-594 in Lipopolysaccharide Micelles by NMR Spectroscopy.,Bhunia A, Ramamoorthy A, Bhattacharjya S Chemistry. 2009 Jan 29;15(9):2036-2040. PMID:19180607<ref>PMID:19180607</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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The line below this paragraph, {{ABSTRACT_PUBMED_19180607}}, adds the Publication Abstract to the page
<div class="pdbe-citations 2k98" style="background-color:#fffaf0;"></div>
(as it appears on PubMed at http://www.pubmed.gov), where 19180607 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_19180607}}
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</StructureSection>
==About this Structure==
[[Category: Large Structures]]
2K98 is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K98 OCA].
[[Category: Bhattacharjya S]]
 
[[Category: Bhunia A]]
==Reference==
[[Category: Ramamoorthy A]]
<ref group="xtra">PMID:19180607</ref><references group="xtra"/>
[[Category: Bhattacharjya, S.]]
[[Category: Bhunia, A.]]
[[Category: Ramamoorthy, A.]]
[[Category: Antimicrobial peptide]]
[[Category: Antimicrobial protein]]
[[Category: Lp]]
[[Category: Msi-594]]
[[Category: Nmr]]
[[Category: Trnoe]]
 
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