3ebe: Difference between revisions

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{{Seed}}
[[Image:3ebe.png|left|200px]]


<!--
==Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain==
The line below this paragraph, containing "STRUCTURE_3ebe", creates the "Structure Box" on the page.
<StructureSection load='3ebe' size='340' side='right'caption='[[3ebe]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ebe]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3EBE FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_3ebe|  PDB=3ebe  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ebe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ebe OCA], [https://pdbe.org/3ebe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ebe RCSB], [https://www.ebi.ac.uk/pdbsum/3ebe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ebe ProSAT]</span></td></tr>
 
</table>
===Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain===
== Function ==
 
[https://www.uniprot.org/uniprot/MCM10_XENLA MCM10_XENLA] Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. Additionally, plays a role in preventing DNA damage during replication (By similarity).<ref>PMID:11864598</ref>  
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_19081065}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 19081065 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eb/3ebe_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_19081065}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
3EBE is a 3 chains structure with sequences from [http://en.wikipedia.org/wiki/Xenopus_laevis Xenopus laevis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3EBE OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3ebe ConSurf].
 
<div style="clear:both"></div>
==Reference==
== References ==
<ref group="xtra">PMID:19081065</ref><references group="xtra"/>
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Xenopus laevis]]
[[Category: Xenopus laevis]]
[[Category: Eichman, B F.]]
[[Category: Eichman BF]]
[[Category: Warren, E M.]]
[[Category: Warren EM]]
[[Category: Ccch]]
[[Category: Dna replication]]
[[Category: Metal-binding]]
[[Category: Nucleus]]
[[Category: Ob-fold]]
[[Category: Zinc]]
[[Category: Zinc finger]]
[[Category: Zinc-finger]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 12:03:02 2010''

Latest revision as of 09:46, 21 February 2024

Crystal structure of xenopus laevis replication initiation factor MCM10 internal domain

3ebe, resolution 2.30Å

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