3mn3: Difference between revisions

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{{Seed}}
[[Image:3mn3.png|left|200px]]


<!--
==An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1==
The line below this paragraph, containing "STRUCTURE_3mn3", creates the "Structure Box" on the page.
<StructureSection load='3mn3' size='340' side='right'caption='[[3mn3]], [[Resolution|resolution]] 2.38&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3mn3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MN3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3MN3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.38&#8491;</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3mn3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3mn3 OCA], [https://pdbe.org/3mn3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3mn3 RCSB], [https://www.ebi.ac.uk/pdbsum/3mn3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3mn3 ProSAT]</span></td></tr>
{{STRUCTURE_3mn3|  PDB=3mn3  |  SCENE=  }}
</table>
 
== Function ==
===An inhibited conformation for the protein kinase domain of the Saccharomyces cerevisiae AMPK homolog Snf1===
[https://www.uniprot.org/uniprot/SNF1_YEAST SNF1_YEAST] Essential for release from glucose repression. It interacts and has functional relationship to the regulatory protein SNF4. Could phosphorylate CAT8. Phosphorylates histone H3 to form H3S10ph, which promotes H3K14ac formation, and which is required for transcriptional activation through TBP recruitment to the promoters.<ref>PMID:15719021</ref>  
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_20823513}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 20823513 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/mn/3mn3_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_20823513}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3mn3 ConSurf].
3MN3 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3MN3 OCA].  
<div style="clear:both"></div>
 
== References ==
==Reference==
<references/>
<ref group="xtra">PMID:20823513</ref><references group="xtra"/>
__TOC__
[[Category: Non-specific serine/threonine protein kinase]]
</StructureSection>
[[Category: Large Structures]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Amodeo, G A.]]
[[Category: Amodeo GA]]
[[Category: Rudolph, M J.]]
[[Category: Rudolph MJ]]
[[Category: Tong, L.]]
[[Category: Tong L]]
[[Category: Autoinhibitory region]]
[[Category: Kinase domain]]
[[Category: Snf1]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Sep 22 14:17:18 2010''
Retrieved from "https://proteopedia.org/3mn3"