3otd: Difference between revisions
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New page: '''Unreleased structure''' The entry 3otd is ON HOLD Authors: Hyde, S.J., Eckenroth, B.E., Doublie, S. Description: Crystal structure of human tRNAHis guanylyltransferase (Thg1)-NaI de... |
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==Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative== | |||
<StructureSection load='3otd' size='340' side='right'caption='[[3otd]], [[Resolution|resolution]] 2.28Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3otd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTD FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otd OCA], [https://pdbe.org/3otd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otd RCSB], [https://www.ebi.ac.uk/pdbsum/3otd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otd ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/THG1_HUMAN THG1_HUMAN] Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. This step is essential for proper recognition of the tRNA and for the fidelity of protein synthesis.<ref>PMID:21059936</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Doublie S]] | |||
[[Category: Eckenroth BE]] | |||
[[Category: Hyde SJ]] | |||
Latest revision as of 10:36, 21 February 2024
Crystal structure of human tRNAHis guanylyltransferase (Thg1)- NaI derivative
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