3otm: Difference between revisions
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New page: '''Unreleased structure''' The entry 3otm is ON HOLD Authors: Domsic, J.F., Robbins, A.H., McKenna, R. Description: Crystal structures of gamma-carbonic anhydrase mutants from Methanos... |
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==Crystal structures of wild-type gamma-carbonic anhydrase from Methanosarcina thermophila== | |||
<StructureSection load='3otm' size='340' side='right'caption='[[3otm]], [[Resolution|resolution]] 1.50Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3otm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanosarcina_thermophila Methanosarcina thermophila]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OTM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OTM FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3otm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3otm OCA], [https://pdbe.org/3otm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3otm RCSB], [https://www.ebi.ac.uk/pdbsum/3otm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3otm ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/CAH_METTT CAH_METTT] Reversible hydration of carbon dioxide. Important for growth on acetate (PubMed:8041719). As a probably extracellular enzyme, it may support a H(+)/CH(3)COO(-) symport mechanism and/or conversion of CO(2) to HCO(3)(-), removing excess CO(2) produced by growth on acetate (Probable).<ref>PMID:8041719</ref> <ref>PMID:10924115</ref> <ref>PMID:8041719</ref> <ref>PMID:8665839</ref> | |||
==See Also== | |||
*[[Carbonic anhydrase 3D structures|Carbonic anhydrase 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Methanosarcina thermophila]] | |||
[[Category: Domsic JF]] | |||
[[Category: McKenna R]] | |||
[[Category: Robbins AH]] | |||
