3n4p: Difference between revisions

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{{Seed}}
[[Image:3n4p.jpg|left|200px]]


<!--
==Human cytomegalovirus terminase nuclease domain==
The line below this paragraph, containing "STRUCTURE_3n4p", creates the "Structure Box" on the page.
<StructureSection load='3n4p' size='340' side='right'caption='[[3n4p]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3n4p]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human_herpesvirus_5_strain_Towne Human herpesvirus 5 strain Towne]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3N4P FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3n4p| PDB=3n4p |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3n4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3n4p OCA], [https://pdbe.org/3n4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3n4p RCSB], [https://www.ebi.ac.uk/pdbsum/3n4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3n4p ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TRM3_HCMVA TRM3_HCMVA] Component of the molecular motor that translocates genomic DNA in empty capsid during DNA packaging. Heterodimerizes with small terminase protein to be docked on capsid portal protein. The latter forms a ring in which genomic DNA in translocated into the capsid. May have or induce an endonuclease activity to cleave the genome concatemer after encapsidation (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/n4/3n4p_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3n4p ConSurf].
<div style="clear:both"></div>


===Human cytomegalovirus terminase nuclease domain===
==See Also==
 
*[[Terminase 3D Structures|Terminase 3D Structures]]
 
__TOC__
<!--
</StructureSection>
The line below this paragraph, {{ABSTRACT_PUBMED_20805464}}, adds the Publication Abstract to the page
[[Category: Human herpesvirus 5 strain Towne]]
(as it appears on PubMed at http://www.pubmed.gov), where 20805464 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Arnan C]]
{{ABSTRACT_PUBMED_20805464}}
[[Category: Blanco AG]]
 
[[Category: Coll M]]
==About this Structure==
[[Category: Hart DJ]]
3N4P is a 4 chains structure with sequences from [http://en.wikipedia.org/wiki/Human_herpesvirus_5 Human herpesvirus 5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3N4P OCA].
[[Category: Mas PJ]]
 
[[Category: Nadal M]]
==Reference==
[[Category: Sola M]]
<ref group="xtra">PMID:20805464</ref><references group="xtra"/>
[[Category: Human herpesvirus 5]]
[[Category: Arnan, C.]]
[[Category: Blanco, A G.]]
[[Category: Coll, M.]]
[[Category: Hart, D J.]]
[[Category: Mas, P J.]]
[[Category: Nadal, M.]]
[[Category: Sola, M.]]
[[Category: Dna binding protein]]
[[Category: Dna packaging]]
[[Category: Hcmv]]
[[Category: Herpesvirus]]
[[Category: Human cytomegalovirus]]
[[Category: Nuclease]]
[[Category: Terminase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct  6 06:06:08 2010''

Latest revision as of 10:27, 21 February 2024

Human cytomegalovirus terminase nuclease domain

3n4p, resolution 2.15Å

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