2l4f: Difference between revisions
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New page: '''Unreleased structure''' The entry 2l4f is ON HOLD Authors: Burschowsky, D., Mattle, D., Rudolf, F., Peter, M., Wider, G. Description: NMR structure of the UBA domain of S. cerevisia... |
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==NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin== | |||
<StructureSection load='2l4f' size='340' side='right'caption='[[2l4f]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2l4f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2L4F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2L4F FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2l4f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2l4f OCA], [https://pdbe.org/2l4f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2l4f RCSB], [https://www.ebi.ac.uk/pdbsum/2l4f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2l4f ProSAT]</span></td></tr> | |||
'' | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/DCN1_YEAST DCN1_YEAST] Required for neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity. Does not act by preventing deneddylation, but rather facilitates neddylation, possibly by acting with HRT1/RBX1 to recruit the Nedd8-charged E2 UBC12 to the cullin component of SCF-type complexes.<ref>PMID:15988528</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Saccharomyces cerevisiae]] | |||
[[Category: Burschowsky D]] | |||
[[Category: Mattle D]] | |||
[[Category: Peter M]] | |||
[[Category: Rudolf F]] | |||
[[Category: Wider G]] | |||
Latest revision as of 05:38, 15 May 2024
NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin
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