3ob9: Difference between revisions

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[[Image:3ob9.jpg|left|200px]]


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==Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution==
The line below this paragraph, containing "STRUCTURE_3ob9", creates the "Structure Box" on the page.
<StructureSection load='3ob9' size='340' side='right'caption='[[3ob9]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ob9]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OB9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OB9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NHE:2-[N-CYCLOHEXYLAMINO]ETHANE+SULFONIC+ACID'>NHE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3ob9|  PDB=3ob9  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ob9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ob9 OCA], [https://pdbe.org/3ob9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ob9 RCSB], [https://www.ebi.ac.uk/pdbsum/3ob9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ob9 ProSAT]</span></td></tr>
 
</table>
===Structure of the human MSL3 chromo-barrel domain at 2.5 Angstrom resolution===
== Function ==
 
[https://www.uniprot.org/uniprot/MS3L1_HUMAN MS3L1_HUMAN] May be involved in chromatin remodeling and transcriptional regulation. May have a role in X inactivation. Component of the MSL complex which is responsible for the majority of histone H4 acetylation at 'Lys-16' which is implicated in the formation of higher-order chromatin structure. Specifically recognizes histone H4 monomethylated at 'Lys-20' (H4K20Me1) in a DNA-dependent manner and is proposed to be involved in chromosomal targeting of the MSL complex.<ref>PMID:16227571</ref> <ref>PMID:20018852</ref> <ref>PMID:20657587</ref> <ref>PMID:20943666</ref>
 
== References ==
==About this Structure==
<references/>
3OB9 is a 5 chains structure with sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OB9 OCA].  
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ferhatoglu, Y.]]
[[Category: Large Structures]]
[[Category: Moore, S A.]]
[[Category: Ferhatoglu Y]]
[[Category: Chromo]]
[[Category: Moore SA]]
[[Category: Chromo-barrel]]
[[Category: Chromodomain]]
[[Category: Histone h4k20me1]]
[[Category: Histone tail]]
[[Category: Methyllysine binding]]
[[Category: Nucleosome recognition]]
[[Category: Nucleus]]
[[Category: Transcription regulator]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Oct 13 10:50:20 2010''