3ogl: Difference between revisions

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[[Image:3ogl.jpg|left|200px]]


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==Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron==
The line below this paragraph, containing "STRUCTURE_3ogl", creates the "Structure Box" on the page.
<StructureSection load='3ogl' size='340' side='right'caption='[[3ogl]], [[Resolution|resolution]] 3.18&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3ogl]] is a 23 chain structure with sequence from [https://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3OGL FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.18&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7JA:N-({(1R,2S)-3-OXO-2-[(2Z)-PENT-2-EN-1-YL]CYCLOPENTYL}ACETYL)-L-ISOLEUCINE'>7JA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3ogl|  PDB=3ogl  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ogl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ogl OCA], [https://pdbe.org/3ogl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ogl RCSB], [https://www.ebi.ac.uk/pdbsum/3ogl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ogl ProSAT]</span></td></tr>
 
</table>
===Structure of COI1-ASK1 in complex with JA-isoleucine and the JAZ1 degron===
== Function ==
 
[https://www.uniprot.org/uniprot/COI1_ARATH COI1_ARATH] Required for jasmonate-regulated plant fertility and defense processes, and for coronatine and/or other elicitors perceptions/responses. Seems to not be required for meiosis. Required for the regulation of some genes induced by wounding, but not for all. Component of SCF(COI1) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (probably including the ribulose bisphosphate carboxylase small chain 1B RBCS-1B and the histone deacetylase HDA6). These SCF complexes play crucial roles in regulating response to jasmonate, and their interactions with the COP9 signalosome (CSN) appear to be important for their activity. Interacts with TIFY10A and inositol pentakisphosphate to form a high-affinity jasmonates coreceptor. Involved in the regulation of plant gene expression during plant-pathogen interactions with Pseudomonas syringae and Alternaria brassicicola.<ref>PMID:9582125</ref> <ref>PMID:12244256</ref> <ref>PMID:10810145</ref> <ref>PMID:12172836</ref> <ref>PMID:12172031</ref> <ref>PMID:12445118</ref> <ref>PMID:12724535</ref> <ref>PMID:12805591</ref> <ref>PMID:14756769</ref>
 
== References ==
==About this Structure==
<references/>
3OGL is a 23 chains structure with sequences from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3OGL OCA].  
__TOC__
</StructureSection>
[[Category: Arabidopsis thaliana]]
[[Category: Arabidopsis thaliana]]
[[Category: Ben-Nissan, G.]]
[[Category: Large Structures]]
[[Category: Browse, J.]]
[[Category: Ben-Nissan G]]
[[Category: He, S Y.]]
[[Category: Browse J]]
[[Category: Hinds, T R.]]
[[Category: He SY]]
[[Category: Howe, G A.]]
[[Category: Hinds TR]]
[[Category: Hsu, F.]]
[[Category: Howe GA]]
[[Category: Mao, H.]]
[[Category: Hsu F]]
[[Category: Rizo, J.]]
[[Category: Mao H]]
[[Category: Sharon, M.]]
[[Category: Rizo J]]
[[Category: Sheard, L B.]]
[[Category: Sharon M]]
[[Category: Tan, X.]]
[[Category: Sheard LB]]
[[Category: Withers, J.]]
[[Category: Tan X]]
[[Category: Zheng, N.]]
[[Category: Withers J]]
[[Category: Leucine-rich repeat]]
[[Category: Zheng N]]
[[Category: Protein binding]]
[[Category: Scf]]
[[Category: Ubiquitin ligase]]
 
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