3p5p: Difference between revisions
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New page: '''Unreleased structure''' The entry 3p5p is ON HOLD Authors: Koksal, M., Christianson, D.W. Description: Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) '... |
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==Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate== | |||
<StructureSection load='3p5p' size='340' side='right'caption='[[3p5p]], [[Resolution|resolution]] 1.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3p5p]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_brevifolia Taxus brevifolia]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3P5P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3P5P FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.816Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A3C:2-(METHYL{2-[(1S,4AS,8AS)-5,5,8A-TRIMETHYL-2-METHYLIDENEDECAHYDRONAPHTHALEN-1-YL]ETHYL}AMINO)ETHYL+TRIHYDROGEN+DIPHOSPHATE'>A3C</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3p5p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3p5p OCA], [https://pdbe.org/3p5p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3p5p RCSB], [https://www.ebi.ac.uk/pdbsum/3p5p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3p5p ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TASY_TAXBR TASY_TAXBR] Catalyzes the cyclization of the ubiquitous isoprenoid intermediate geranylgeranyl diphosphate to taxa-4,11-diene, the parent olefin with a taxane skeleton. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Taxus brevifolia]] | |||
[[Category: Christianson DW]] | |||
[[Category: Koksal M]] | |||
Latest revision as of 10:38, 21 February 2024
Crystal Structure of Taxadiene Synthase from Pacific Yew (Taxus brevifolia) in complex with Mg2+ and 13-aza-13,14-dihydrocopalyl diphosphate
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