3m4z: Difference between revisions

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[[Image:3m4z.jpg|left|200px]]


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==Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site==
The line below this paragraph, containing "STRUCTURE_3m4z", creates the "Structure Box" on the page.
<StructureSection load='3m4z' size='340' side='right'caption='[[3m4z]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3m4z]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3M4Z FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
{{STRUCTURE_3m4z|  PDB=3m4z  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3m4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3m4z OCA], [https://pdbe.org/3m4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3m4z RCSB], [https://www.ebi.ac.uk/pdbsum/3m4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3m4z ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CPFC_BACSU CPFC_BACSU] Involved in coproporphyrin-dependent heme b biosynthesis (PubMed:25646457, PubMed:25908396). Catalyzes the insertion of ferrous iron into coproporphyrin III to form Fe-coproporphyrin III (PubMed:25646457, PubMed:25908396). It can also insert iron into protoporphyrin IX (PubMed:1459957, PubMed:8119288, PubMed:21052751, PubMed:25646457). Has weaker activity with 2,4 disulfonate, deuteroporphyrin and 2,4 hydroxyethyl (PubMed:25646457, PubMed:12761666). In vitro, can also use Zn(2+) or Cu(2+) (PubMed:8119288, PubMed:16140324, PubMed:21052751, PubMed:12761666).<ref>PMID:12761666</ref> <ref>PMID:1459957</ref> <ref>PMID:16140324</ref> <ref>PMID:21052751</ref> <ref>PMID:25646457</ref> <ref>PMID:25826316</ref> <ref>PMID:25908396</ref> <ref>PMID:8119288</ref>  


===Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site===
==See Also==
 
*[[Ferrochelatase 3D structures|Ferrochelatase 3D structures]]
 
== References ==
==About this Structure==
<references/>
3M4Z is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3M4Z OCA].
__TOC__
</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
[[Category: Ferrochelatase]]
[[Category: Large Structures]]
[[Category: Al-Karadaghi, S.]]
[[Category: Al-Karadaghi S]]
[[Category: Hansson, M.]]
[[Category: Hansson M]]
[[Category: Hansson, M D.]]
[[Category: Hansson MD]]
[[Category: Soderberg, C A.G.]]
[[Category: Soderberg CAG]]
[[Category: Sreekanth, R.]]
[[Category: Sreekanth R]]
[[Category: Cobalt]]
[[Category: Heme biosynthesis]]
[[Category: Iron]]
[[Category: Lyase]]
[[Category: Metal-binding]]
[[Category: Pi-helix]]
[[Category: Porphyrin biosynthesis]]
[[Category: Rossman fold]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Nov 10 06:48:36 2010''